Gene Ontology

Gene Info

• Species: Rat (Rattus norvegicus)
• GeneID: 304109
• Symbol: Tiam1
• Description: TIAM Rac1 associated GEF 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
304109	GO:0003300	IMP	involved_in	cardiac muscle hypertrophy	22564263	Process
304109	GO:0010976	IMP	involved_in	positive regulation of neuron projection development	20333299	Process
304109	GO:0030335	IMP	involved_in	positive regulation of cell migration	24123220	Process
304109	GO:0042220	IEP	involved_in	response to cocaine	23745104	Process
304109	GO:0043507	IMP	involved_in	positive regulation of JUN kinase activity	16203995	Process
304109	GO:0050772	IMP	involved_in	positive regulation of axonogenesis	11264310	Process
304109	GO:0061003	IMP	involved_in	positive regulation of dendritic spine morphogenesis	16474385	Process
304109	GO:0061178	IMP	involved_in	regulation of insulin secretion involved in cellular response to glucose stimulus	18930714	Process
304109	GO:0070372	IMP	involved_in	regulation of ERK1 and ERK2 cascade	22564263	Process
304109	GO:0072657	IMP	involved_in	protein localization to membrane	18930714	Process
304109	GO:0090630	IMP	involved_in	activation of GTPase activity	18930714	Process
304109	GO:0098989	IMP	involved_in	NMDA selective glutamate receptor signaling pathway	15721239	Process
304109	GO:0099175	IDA	involved_in	regulation of postsynapse organization	15721239	Process
304109	GO:0099175	IMP	involved_in	regulation of postsynapse organization	15721239	Process
304109	GO:1904268	IMP	involved_in	positive regulation of Schwann cell chemotaxis	16203995	Process
304109	GO:1905274	IDA	involved_in	regulation of modification of postsynaptic actin cytoskeleton	15721239	Process
304109	GO:1905274	IMP	involved_in	regulation of modification of postsynaptic actin cytoskeleton	15721239	Process
304109	GO:1990138	IMP	involved_in	neuron projection extension	20333299	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
304109	GO:0005515	IPI	enables	protein binding	12446731,15899863,16474385,23595754	Function
304109	GO:0008017	IDA	enables	microtubule binding	11264310	Function
304109	GO:0030971	IPI	enables	receptor tyrosine kinase binding	16801538	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
304109	GO:0005874	IDA	colocalizes_with	microtubule	11264310	Component
304109	GO:0014069	IDA	located_in	postsynaptic density	15721239	Component
304109	GO:0032587	IDA	located_in	ruffle membrane	12446731	Component
304109	GO:0036477	IDA	located_in	somatodendritic compartment	23300879	Component
304109	GO:0043025	IDA	located_in	neuronal cell body	11264310	Component
304109	GO:0043197	IDA	located_in	dendritic spine	16474385	Component
304109	GO:0044295	IDA	located_in	axonal growth cone	11264310	Component
304109	GO:0044304	IDA	located_in	main axon	11264310	Component
304109	GO:0098978	IDA	is_active_in	glutamatergic synapse	15721239	Component
304109	GO:0098978	IMP	is_active_in	glutamatergic synapse	15721239	Component
304109	GO:0099147	IDA	is_active_in	extrinsic component of postsynaptic density membrane	15721239	Component