Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3087
  • Symbol: HHEX
  • Description: hematopoietically expressed homeobox

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3087 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 10871399,15016828 Process
3087 GO:0006406 IDA involved_in mRNA export from nucleus 12554669 Process
3087 GO:0016973 IMP involved_in poly(A)+ mRNA export from nucleus 12554669 Process
3087 GO:0034504 IDA involved_in protein localization to nucleus 18713067 Process
3087 GO:0045736 IDA involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity 12554669 Process
3087 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 10871399,15016828 Process
3087 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 20028982 Process
3087 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 12655000 Process
3087 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 20028982 Process
3087 GO:0070663 IDA involved_in regulation of leukocyte proliferation 12554669 Process
3087 GO:0071103 IDA involved_in DNA conformation change 18755198 Process
3087 GO:0090263 IMP involved_in positive regulation of canonical Wnt signaling pathway 20028982 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3087 GO:0000976 IDA enables transcription cis-regulatory region binding 18755198 Function
3087 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 15016828 Function
3087 GO:0001227 IDA enables DNA-binding transcription repressor activity, RNA polymerase II-specific 15016828 Function
3087 GO:0001228 IMP enables DNA-binding transcription activator activity, RNA polymerase II-specific 20028982 Function
3087 GO:0005515 IPI enables protein binding 10597310,12826010,19324893,20028982,25416956,32296183,32814053..... Function
3087 GO:0008190 IDA enables eukaryotic initiation factor 4E binding 12554669 Function
3087 GO:0008301 IDA enables DNA binding, bending 18755198 Function
3087 GO:0042803 IPI enables protein homodimerization activity 16540119 Function
3087 GO:0043565 IDA enables sequence-specific DNA binding 10871399 Function
3087 GO:0140297 IDA enables DNA-binding transcription factor binding 15187083 Function
3087 GO:0140297 IPI enables DNA-binding transcription factor binding 15016828 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3087 GO:0005634 IDA located_in nucleus 12554669,12588764,12826010 Component
3087 GO:0005737 IDA located_in cytoplasm 12554669,12826010 Component
3087 GO:0032993 IDA part_of protein-DNA complex 18755198 Component