Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3106
  • Symbol: HLA-B
  • Description: major histocompatibility complex, class I, B

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3106 GO:0001916 IDA involved_in positive regulation of T cell mediated cytotoxicity 2420472 Process
3106 GO:0002486 IDA involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 22031944 Process
3106 GO:0002667 IMP involved_in regulation of T cell anergy 20008523 Process
3106 GO:0006955 IMP involved_in immune response 22321387 Process
3106 GO:0016045 IMP involved_in detection of bacterium 22321387 Process
3106 GO:0032655 IMP involved_in regulation of interleukin-12 production 20008523 Process
3106 GO:0032675 IMP involved_in regulation of interleukin-6 production 20008523 Process
3106 GO:0042270 IDA involved_in protection from natural killer cell mediated cytotoxicity 2784569,8046333,18502829 Process
3106 GO:2001198 IMP involved_in regulation of dendritic cell differentiation 20008523 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3106 GO:0005102 IPI enables signaling receptor binding 8046333,20008523 Function
3106 GO:0005515 IPI enables protein binding 19858347,26439010,27649529,28546555 Function
3106 GO:0042605 IDA enables peptide antigen binding 22031944,23646949 Function
3106 GO:0046977 IDA NOT enables TAP binding 8617941 Function
3106 GO:0046977 IDA enables TAP binding 8617941 Function
3106 GO:0051087 IPI enables protein-folding chaperone binding 15056662 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3106 GO:0005783 IDA located_in endoplasmic reticulum 20946353 Component
3106 GO:0005794 IDA located_in Golgi apparatus 20946353 Component
3106 GO:0009986 HDA located_in cell surface 19581412 Component
3106 GO:0009986 IDA located_in cell surface 9754572,22031944 Component
3106 GO:0016020 HDA located_in membrane 19946888 Component
3106 GO:0042612 IDA part_of MHC class I protein complex 22031944 Component
3106 GO:0070062 HDA located_in extracellular exosome 12519789,19056867,19199708,20458337 Component