Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 319757
  • Symbol: Smo
  • Description: smoothened, frizzled class receptor

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
319757 GO:0000122 IMP acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 19304890 Process
319757 GO:0001503 IMP acts_upstream_of_or_within ossification 11748145 Process
319757 GO:0001570 IMP acts_upstream_of_or_within vasculogenesis 15294868,17881493 Process
319757 GO:0001649 IMP acts_upstream_of_or_within osteoblast differentiation 14973297 Process
319757 GO:0001701 IMP acts_upstream_of_or_within in utero embryonic development 17881493 Process
319757 GO:0001708 IMP acts_upstream_of_or_within cell fate specification 18590716 Process
319757 GO:0001755 IGI acts_upstream_of_or_within neural crest cell migration 16687132 Process
319757 GO:0001942 IMP acts_upstream_of hair follicle development 17199044 Process
319757 GO:0001947 IMP involved_in heart looping 11517919 Process
319757 GO:0002052 IGI acts_upstream_of_or_within positive regulation of neuroblast proliferation 16543460 Process
319757 GO:0002053 IMP acts_upstream_of_or_within positive regulation of mesenchymal cell proliferation 19304890 Process
319757 GO:0003007 IGI acts_upstream_of_or_within heart morphogenesis 16687132 Process
319757 GO:0003140 IMP involved_in determination of left/right asymmetry in lateral mesoderm 11517919 Process
319757 GO:0003323 IMP acts_upstream_of_or_within type B pancreatic cell development 20185815 Process
319757 GO:0006606 IGI acts_upstream_of protein import into nucleus 17043310 Process
319757 GO:0006915 IMP acts_upstream_of apoptotic process 16571630 Process
319757 GO:0006915 IMP acts_upstream_of_or_within apoptotic process 35353806 Process
319757 GO:0007224 IDA acts_upstream_of_or_within smoothened signaling pathway 35353806 Process
319757 GO:0007224 IGI acts_upstream_of_or_within smoothened signaling pathway 17043310 Process
319757 GO:0007224 IMP acts_upstream_of_or_within smoothened signaling pathway 15107405,16136078,17199044,20185815,29487109 Process
319757 GO:0007224 IMP involved_in smoothened signaling pathway 11517919,21177415,27793670 Process
319757 GO:0007228 IMP involved_in positive regulation of hh target transcription factor activity 11517919 Process
319757 GO:0007368 IMP acts_upstream_of_or_within determination of left/right symmetry 12421714,15755804 Process
319757 GO:0007371 IMP involved_in ventral midline determination 11517919 Process
319757 GO:0007389 IMP acts_upstream_of_or_within pattern specification process 15107405 Process
319757 GO:0007405 IGI acts_upstream_of neuroblast proliferation 16543460 Process
319757 GO:0007417 IGI acts_upstream_of_or_within central nervous system development 12435628 Process
319757 GO:0007494 IMP involved_in midgut development 11517919 Process
319757 GO:0008283 IMP acts_upstream_of cell population proliferation 12403705,19124651 Process
319757 GO:0008284 IMP acts_upstream_of_or_within positive regulation of cell population proliferation 19124651 Process
319757 GO:0009952 IMP acts_upstream_of_or_within anterior/posterior pattern specification 22987639 Process
319757 GO:0009953 IMP acts_upstream_of_or_within dorsal/ventral pattern formation 15755804,16571630 Process
319757 GO:0010467 IDA acts_upstream_of_or_within gene expression 23201751 Process
319757 GO:0010468 IGI acts_upstream_of_or_within regulation of gene expression 18590716 Process
319757 GO:0010628 IMP acts_upstream_of_or_within positive regulation of gene expression 23680462 Process
319757 GO:0010628 IMP involved_in positive regulation of gene expression 16396903 Process
319757 GO:0010629 IMP involved_in negative regulation of gene expression 16396903 Process
319757 GO:0021542 IMP acts_upstream_of_or_within dentate gyrus development 18297065 Process
319757 GO:0021696 IMP acts_upstream_of_or_within cerebellar cortex morphogenesis 16571625 Process
319757 GO:0021794 IMP acts_upstream_of_or_within thalamus development 19357274 Process
319757 GO:0021904 IMP acts_upstream_of_or_within dorsal/ventral neural tube patterning 18590716 Process
319757 GO:0021910 IMP acts_upstream_of_or_within smoothened signaling pathway involved in ventral spinal cord patterning 19286674 Process
319757 GO:0021910 IMP involved_in smoothened signaling pathway involved in ventral spinal cord patterning 21209331 Process
319757 GO:0021938 IMP acts_upstream_of_or_within smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 16571625 Process
319757 GO:0021953 IMP acts_upstream_of_or_within central nervous system neuron differentiation 16571630 Process
319757 GO:0021987 IMP acts_upstream_of_or_within cerebral cortex development 23680462 Process
319757 GO:0030855 IMP acts_upstream_of epithelial cell differentiation 17199044 Process
319757 GO:0030857 IMP acts_upstream_of_or_within negative regulation of epithelial cell differentiation 17199044 Process
319757 GO:0031069 IMP acts_upstream_of_or_within hair follicle morphogenesis 17199044 Process
319757 GO:0034504 IMP acts_upstream_of_or_within protein localization to nucleus 19952108 Process
319757 GO:0035264 IGI acts_upstream_of_or_within multicellular organism growth 18590716 Process
319757 GO:0035264 IMP acts_upstream_of_or_within multicellular organism growth 18590716 Process
319757 GO:0040018 IMP involved_in positive regulation of multicellular organism growth 24548465 Process
319757 GO:0042307 IGI acts_upstream_of_or_within positive regulation of protein import into nucleus 17043310 Process
319757 GO:0042475 IMP acts_upstream_of_or_within odontogenesis of dentin-containing tooth 12403705,17199044 Process
319757 GO:0043066 IMP acts_upstream_of_or_within negative regulation of apoptotic process 16571630 Process
319757 GO:0043392 IGI acts_upstream_of_or_within negative regulation of DNA binding 16396903 Process
319757 GO:0043392 IMP involved_in negative regulation of DNA binding 16396903 Process
319757 GO:0045880 IMP acts_upstream_of_or_within positive regulation of smoothened signaling pathway 16459297 Process
319757 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 24548465 Process
319757 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 24548465 Process
319757 GO:0045944 IMP acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 15906375,19304890 Process
319757 GO:0046622 IMP involved_in positive regulation of organ growth 24548465 Process
319757 GO:0048143 IMP acts_upstream_of_or_within astrocyte activation 23680462 Process
319757 GO:0048468 IMP acts_upstream_of_or_within cell development 12403705 Process
319757 GO:0048565 IMP acts_upstream_of_or_within digestive tract development 19619492 Process
319757 GO:0048568 IGI acts_upstream_of_or_within embryonic organ development 24302887 Process
319757 GO:0048589 IMP acts_upstream_of_or_within developmental growth 16571630 Process
319757 GO:0048741 IMP acts_upstream_of_or_within skeletal muscle fiber development 22987639 Process
319757 GO:0048853 IMP involved_in forebrain morphogenesis 11517919 Process
319757 GO:0048873 IDA acts_upstream_of_or_within homeostasis of number of cells within a tissue 23680462 Process
319757 GO:0050673 IMP acts_upstream_of epithelial cell proliferation 12403705 Process
319757 GO:0050679 IMP acts_upstream_of_or_within positive regulation of epithelial cell proliferation 12403705,19304890 Process
319757 GO:0050821 IDA acts_upstream_of_or_within protein stabilization 19124651 Process
319757 GO:0051451 IGI acts_upstream_of_or_within myoblast migration 22987639 Process
319757 GO:0051799 IMP acts_upstream_of_or_within negative regulation of hair follicle development 17199044 Process
319757 GO:0060413 IGI acts_upstream_of_or_within atrial septum morphogenesis 22898775 Process
319757 GO:0060644 IMP acts_upstream_of_or_within mammary gland epithelial cell differentiation 17199044 Process
319757 GO:0060684 IMP acts_upstream_of_or_within epithelial-mesenchymal cell signaling 19304890 Process
319757 GO:0061053 IMP involved_in somite development 11517919 Process
319757 GO:0061113 IMP acts_upstream_of_or_within pancreas morphogenesis 20185815 Process
319757 GO:0070986 IMP acts_upstream_of_or_within left/right axis specification 9636176 Process
319757 GO:0071397 IEP involved_in cellular response to cholesterol 21931618 Process
319757 GO:0071542 IMP acts_upstream_of_or_within dopaminergic neuron differentiation 16571630 Process
319757 GO:0071929 IMP involved_in alpha-tubulin acetylation 27793670 Process
319757 GO:0072285 IMP involved_in mesenchymal to epithelial transition involved in metanephric renal vesicle formation 16396903 Process
319757 GO:0090190 IMP involved_in positive regulation of branching involved in ureteric bud morphogenesis 16396903 Process
319757 GO:1904672 IMP acts_upstream_of_or_within regulation of somatic stem cell population maintenance 17199044 Process
319757 GO:2000826 IMP involved_in regulation of heart morphogenesis 11517919 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
319757 GO:0005515 IPI enables protein binding 21659505,25644602,35353806 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
319757 GO:0005737 IDA located_in cytoplasm 18488998 Component
319757 GO:0005770 IDA located_in late endosome 35353806 Component
319757 GO:0005783 IDA located_in endoplasmic reticulum 35353806 Component
319757 GO:0005793 IDA located_in endoplasmic reticulum-Golgi intermediate compartment 35353806 Component
319757 GO:0005794 IDA is_active_in Golgi apparatus 35353806 Component
319757 GO:0005794 IDA located_in Golgi apparatus 35353806 Component
319757 GO:0005814 IDA located_in centriole 29038301 Component
319757 GO:0005886 IDA located_in plasma membrane 21931618,35353806 Component
319757 GO:0005929 IDA located_in cilium 16136078,16229832,18488998,19654211,19684112,21209331,21659505..... Component
319757 GO:0005929 IMP is_active_in cilium 27793670 Component
319757 GO:0060170 IDA located_in ciliary membrane 22179047 Component
319757 GO:0097731 IDA located_in 9+0 non-motile cilium 26996322 Component