Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3251
  • Symbol: HPRT1
  • Description: hypoxanthine phosphoribosyltransferase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3251 GO:0000287 IDA enables magnesium ion binding 10360366 Function
3251 GO:0004422 IDA enables hypoxanthine phosphoribosyltransferase activity 6300847,9521733,19527031 Function
3251 GO:0005515 IPI enables protein binding 16189514,19060904,25416956,25910212,31515488,32296183,32814053..... Function
3251 GO:0042802 IPI enables identical protein binding 8044844,25416956,25502805,31515488,32296183 Function
3251 GO:0052657 IDA enables guanine phosphoribosyltransferase activity 4208686,19527031 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3251 GO:0005737 IDA located_in cytoplasm 6300847 Component
3251 GO:0005829 IDA located_in cytosol Component
3251 GO:0070062 HDA located_in extracellular exosome 20458337 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3251 GO:0006164 IMP involved_in purine nucleotide biosynthetic process 9824441 Process
3251 GO:0006166 IMP involved_in purine ribonucleoside salvage 9824441 Process
3251 GO:0006178 IDA involved_in guanine salvage 19527031 Process
3251 GO:0032263 IDA involved_in GMP salvage 4208686 Process
3251 GO:0043103 IDA involved_in hypoxanthine salvage 19527031 Process
3251 GO:0045964 IMP involved_in positive regulation of dopamine metabolic process 8643611 Process
3251 GO:0046038 IDA involved_in GMP catabolic process 19527031 Process
3251 GO:0046040 IDA involved_in IMP metabolic process 19527031 Process
3251 GO:0046100 IMP involved_in hypoxanthine metabolic process 9824441 Process
3251 GO:0051289 IPI involved_in protein homotetramerization 15990111 Process