Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3280
• Symbol: HES1
• Description: hes family bHLH transcription factor 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3280	GO:0000122	IDA	involved_in	negative regulation of transcription by RNA polymerase II	12032823,12535671	Process
3280	GO:0007219	IDA	involved_in	Notch signaling pathway	16160079	Process
3280	GO:0007219	IMP	involved_in	Notch signaling pathway	19682396	Process
3280	GO:0045892	IDA	involved_in	negative regulation of DNA-templated transcription	12535671	Process
3280	GO:0097150	IEP	involved_in	neuronal stem cell population maintenance	19682396	Process
3280	GO:2000737	IMP	involved_in	negative regulation of stem cell differentiation	19682396	Process
3280	GO:2000974	IMP	involved_in	negative regulation of pro-B cell differentiation	12032823	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3280	GO:0005515	IPI	enables	protein binding	12535671	Function
3280	GO:0042826	IPI	enables	histone deacetylase binding	12535671	Function
3280	GO:1990837	IDA	enables	sequence-specific double-stranded DNA binding	28473536	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3280	GO:0005654	IDA	located_in	nucleoplasm		Component