Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3356
  • Symbol: HTR2A
  • Description: 5-hydroxytryptamine receptor 2A

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3356 GO:0001587 IDA enables Gq/11-coupled serotonin receptor activity 18703043 Function
3356 GO:0004993 IDA enables G protein-coupled serotonin receptor activity 7582481,15862800 Function
3356 GO:0005515 IPI enables protein binding 14988405,28258217,30157263 Function
3356 GO:0042802 IPI enables identical protein binding 19279328,28258217 Function
3356 GO:0051378 IDA enables serotonin binding 7582481,15831837,15862800,18703043,19057895 Function
3356 GO:0071886 IDA enables 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding 19057895 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3356 GO:0005886 IDA located_in plasma membrane 15862800,18703043 Component
3356 GO:0098666 IDA part_of G protein-coupled serotonin receptor complex 18703043 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3356 GO:0006874 IDA involved_in intracellular calcium ion homeostasis 16517693,19057895 Process
3356 GO:0007202 IDA involved_in activation of phospholipase C activity 16517693 Process
3356 GO:0009410 IDA involved_in response to xenobiotic stimulus 15862800 Process
3356 GO:0010513 IDA involved_in positive regulation of phosphatidylinositol biosynthetic process 19057895 Process
3356 GO:0014065 IDA involved_in phosphatidylinositol 3-kinase signaling 16517693 Process
3356 GO:0051209 IDA involved_in release of sequestered calcium ion into cytosol 15862800 Process
3356 GO:0051209 IMP involved_in release of sequestered calcium ion into cytosol 18703043 Process
3356 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 19057895 Process
3356 GO:0098664 IDA involved_in G protein-coupled serotonin receptor signaling pathway 18703043 Process
3356 GO:0098664 IMP involved_in G protein-coupled serotonin receptor signaling pathway 18703043 Process