Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3357
  • Symbol: HTR2B
  • Description: 5-hydroxytryptamine receptor 2B

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3357 GO:0001587 IDA enables Gq/11-coupled serotonin receptor activity 18703043 Function
3357 GO:0001965 IMP enables G-protein alpha-subunit binding 15625277 Function
3357 GO:0004993 IDA enables G protein-coupled serotonin receptor activity 7582481,7926008,12970106,15862800 Function
3357 GO:0004993 IMP enables G protein-coupled serotonin receptor activity 15625277 Function
3357 GO:0005515 IPI enables protein binding 28258217 Function
3357 GO:0051378 IDA enables serotonin binding 7582481,7926008,12970106,15625277,15831837,15862800,17609583,1..... Function

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3357 GO:0001819 IDA involved_in positive regulation of cytokine production 19023134 Process
3357 GO:0001938 IMP involved_in positive regulation of endothelial cell proliferation 19308295 Process
3357 GO:0006874 IDA involved_in intracellular calcium ion homeostasis 16517693,19057895 Process
3357 GO:0007186 IMP involved_in G protein-coupled receptor signaling pathway 15625277 Process
3357 GO:0007202 IDA involved_in activation of phospholipase C activity 16517693,19057895 Process
3357 GO:0007208 IDA involved_in phospholipase C-activating serotonin receptor signaling pathway 12970106 Process
3357 GO:0008284 IDA involved_in positive regulation of cell population proliferation 15625277 Process
3357 GO:0008284 IMP involved_in positive regulation of cell population proliferation 15925089 Process
3357 GO:0009410 IDA involved_in response to xenobiotic stimulus 15862800 Process
3357 GO:0010513 IDA involved_in positive regulation of phosphatidylinositol biosynthetic process 19057895 Process
3357 GO:0014065 IDA involved_in phosphatidylinositol 3-kinase signaling 16517693 Process
3357 GO:0014827 IMP involved_in intestine smooth muscle contraction 7599919,9186750 Process
3357 GO:0016310 IMP involved_in phosphorylation 19308295 Process
3357 GO:0019722 IMP involved_in calcium-mediated signaling 8882600 Process
3357 GO:0019934 IDA involved_in cGMP-mediated signaling 12970106 Process
3357 GO:0042310 IMP involved_in vasoconstriction 15625277 Process
3357 GO:0043123 IEP involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 12761501 Process
3357 GO:0043406 IDA involved_in positive regulation of MAP kinase activity 15625277 Process
3357 GO:0050795 IMP involved_in regulation of behavior 21179162 Process
3357 GO:0051000 IDA involved_in positive regulation of nitric-oxide synthase activity 15625277 Process
3357 GO:0051209 IDA involved_in release of sequestered calcium ion into cytosol 15862800 Process
3357 GO:0051209 IMP involved_in release of sequestered calcium ion into cytosol 8882600,18566482,18703043 Process
3357 GO:0070371 IMP involved_in ERK1 and ERK2 cascade 19308295 Process
3357 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 19057895 Process
3357 GO:0070528 IMP involved_in protein kinase C signaling 20099302 Process
3357 GO:0098664 IDA involved_in G protein-coupled serotonin receptor signaling pathway 7926008 Process
3357 GO:0098664 IMP involved_in G protein-coupled serotonin receptor signaling pathway 18703043 Process

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3357 GO:0005654 IDA located_in nucleoplasm Component
3357 GO:0005737 IDA located_in cytoplasm 15925089 Component
3357 GO:0005886 IDA located_in plasma membrane 7926008,12970106,15625277,15862800,18703043,19023134..... Component
3357 GO:0098666 IDA part_of G protein-coupled serotonin receptor complex 7926008,12970106,15862800,18703043 Component
3357 GO:0098666 IMP part_of G protein-coupled serotonin receptor complex 15625277 Component