Gene Ontology

Gene Info

• Species: Fission yeast (Schizosaccharomyces pombe)
• GeneID: 3361342
• Symbol: sir2
• Description: histone deacetylase, Sirtuin family, NAD-dependent Sir2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3361342	GO:0000122	IEP	involved_in	negative regulation of transcription by RNA polymerase II	17446861	Process
3361342	GO:0031507	EXP	involved_in	heterochromatin formation	23771057	Process
3361342	GO:0031507	IMP	involved_in	heterochromatin formation	15545655	Process
3361342	GO:0040029	IMP	involved_in	epigenetic regulation of gene expression	16079916	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3361342	GO:0000785	IDA	part_of	chromatin	17446861	Component
3361342	GO:0005634	HDA	is_active_in	nucleus	16823372	Component
3361342	GO:0005634	IDA	is_active_in	nucleus	15545655	Component
3361342	GO:0005721	EXP	part_of	pericentric heterochromatin	16079916	Component
3361342	GO:0005721	IDA	part_of	pericentric heterochromatin	15545655,17446861	Component
3361342	GO:0031934	EXP	part_of	mating-type region heterochromatin	16079916	Component
3361342	GO:0031934	IDA	part_of	mating-type region heterochromatin	15545655,17446861	Component
3361342	GO:0033553	EXP	part_of	rDNA heterochromatin	16079916	Component
3361342	GO:0033553	IDA	part_of	rDNA heterochromatin	17446861	Component
3361342	GO:0099115	IDA	is_active_in	chromosome, subtelomeric region	15545655,17446861	Component
3361342	GO:0140720	EXP	part_of	subtelomeric heterochromatin	16079916	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
3361342	GO:0004407	IDA	enables	histone deacetylase activity	12867036	Function
3361342	GO:0031078	IDA	enables	histone H3K14 deacetylase activity	23771057	Function
3361342	GO:0032129	EXP	enables	histone H3K9 deacetylase activity	16079916	Function
3361342	GO:0032129	IDA	enables	histone H3K9 deacetylase activity	23771057	Function
3361342	GO:0034739	IDA	enables	histone H4K16 deacetylase activity	23771057	Function
3361342	GO:0046969	EXP	enables	NAD-dependent histone H3K9 deacetylase activity	17446861	Function
3361342	GO:0046969	IDA	enables	NAD-dependent histone H3K9 deacetylase activity	12867036	Function
3361342	GO:0046970	EXP	enables	NAD-dependent histone H4K16 deacetylase activity	17446861	Function
3361342	GO:0046970	IDA	enables	NAD-dependent histone H4K16 deacetylase activity	12867036	Function
3361342	GO:0070403	IDA	enables	NAD+ binding	12867036	Function
3361342	GO:1990162	IDA	enables	histone H3K4 deacetylase activity	23771057	Function