Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 338
  • Symbol: APOB
  • Description: apolipoprotein B

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
338 GO:0005515 IPI enables protein binding 8245722,16203724,21911577,22580899,24447298,25108285,26224785,..... Function
338 GO:0005543 IDA enables phospholipid binding 7126555 Function
338 GO:0008201 IDA enables heparin binding 16233946 Function
338 GO:0035473 IPI enables lipase binding 9685400 Function
338 GO:0050750 IMP enables low-density lipoprotein particle receptor binding 2563166,15797858 Function
338 GO:0050750 IPI enables low-density lipoprotein particle receptor binding 27477018 Function
338 GO:0120020 IMP enables cholesterol transfer activity 15797858 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
338 GO:0005576 HDA located_in extracellular region 27068509 Component
338 GO:0005737 IDA located_in cytoplasm 22580899 Component
338 GO:0005829 IDA located_in cytosol Component
338 GO:0034359 IDA part_of mature chylomicron 4363408 Component
338 GO:0034361 IDA part_of very-low-density lipoprotein particle 4363408,15308631 Component
338 GO:0034362 IDA part_of low-density lipoprotein particle 4363408 Component
338 GO:0034363 IDA part_of intermediate-density lipoprotein particle 1917954 Component
338 GO:0042627 IDA part_of chylomicron 4363408,8245722 Component
338 GO:0043025 IDA located_in neuronal cell body 22897442 Component
338 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component
338 GO:0070062 HDA located_in extracellular exosome 23533145 Component
338 GO:0070971 IDA located_in endoplasmic reticulum exit site 27138255 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
338 GO:0008203 IMP involved_in cholesterol metabolic process 2563166 Process
338 GO:0009615 IEP involved_in response to virus 16548883 Process
338 GO:0010744 IDA involved_in positive regulation of macrophage derived foam cell differentiation 17244792,18322245,19114110 Process
338 GO:0010884 IDA involved_in positive regulation of lipid storage 18322245 Process
338 GO:0010886 IDA involved_in positive regulation of cholesterol storage 19114110 Process
338 GO:0030301 IMP involved_in cholesterol transport 2563166 Process
338 GO:0034374 IMP involved_in low-density lipoprotein particle remodeling 15797858 Process
338 GO:0034383 IMP involved_in low-density lipoprotein particle clearance 2563166,15797858 Process
338 GO:0042632 IMP involved_in cholesterol homeostasis 2563166 Process