Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 34708
  • Symbol: Sirt1
  • Description: Sirtuin 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
34708 GO:0004407 IDA enables histone deacetylase activity 11281647,16137856 Function
34708 GO:0004407 IMP enables histone deacetylase activity 25578876 Function
34708 GO:0008134 IPI enables transcription factor binding 19366813 Function
34708 GO:0017136 IDA enables NAD-dependent histone deacetylase activity 11812793,12086602,12524341,15498488 Function
34708 GO:0033558 IDA enables protein lysine deacetylase activity 27623778,36459649 Function
34708 GO:0033558 IMP enables protein lysine deacetylase activity 27058248 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
34708 GO:0005634 IDA located_in nucleus 12524341,16137856 Component
34708 GO:0005654 IDA located_in nucleoplasm 16219773 Component
34708 GO:0005737 IDA located_in cytoplasm 12524341 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
34708 GO:0006355 IDA involved_in regulation of DNA-templated transcription 16137856 Process
34708 GO:0006476 IMP involved_in protein deacetylation 27058248 Process
34708 GO:0008340 IMP NOT involved_in determination of adult lifespan 21938067 Process
34708 GO:0008340 IMP involved_in determination of adult lifespan 17159295 Process
34708 GO:0031507 IMP involved_in heterochromatin formation 16219773 Process
34708 GO:0032869 IMP involved_in cellular response to insulin stimulus 27058248 Process
34708 GO:0034983 IDA involved_in peptidyl-lysine deacetylation 27623778 Process
34708 GO:0042981 IMP involved_in regulation of apoptotic process 18562277 Process
34708 GO:0045747 IMP involved_in positive regulation of Notch signaling pathway 27623778 Process
34708 GO:0046331 IMP involved_in lateral inhibition 27623778 Process
34708 GO:0048149 IMP involved_in behavioral response to ethanol 19951294 Process
34708 GO:1901416 IMP involved_in regulation of response to ethanol 27170122 Process
34708 GO:2000253 IGI involved_in positive regulation of feeding behavior 22876196 Process
34708 GO:2000253 IMP involved_in positive regulation of feeding behavior 22876196 Process