Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3516
  • Symbol: RBPJ
  • Description: recombination signal binding protein for immunoglobulin kappa J region

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3516 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 18663143 Process
3516 GO:0007219 IMP involved_in Notch signaling pathway 18663143 Process
3516 GO:0007221 IDA involved_in positive regulation of transcription of Notch receptor target 21102556 Process
3516 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 10713164 Process
3516 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 18663143,20890042 Process
3516 GO:0061314 IMP involved_in Notch signaling involved in heart development 21311046 Process
3516 GO:0061419 IDA involved_in positive regulation of transcription from RNA polymerase II promoter in response to hypoxia 23303788 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3516 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 16691198 Function
3516 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 18663143 Function
3516 GO:0005515 IPI enables protein binding 8627785,9874765,10713164,16510869,16530044,17284587,21102556,2..... Function
3516 GO:0043565 IDA enables sequence-specific DNA binding 23303788 Function
3516 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 16287852 Function
3516 GO:0140297 IDA enables DNA-binding transcription factor binding 23303788 Function
3516 GO:0140297 IPI enables DNA-binding transcription factor binding 16691198 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3516 GO:0002193 IDA part_of MAML1-RBP-Jkappa- ICN1 complex 16510869 Component
3516 GO:0005634 IDA located_in nucleus 9874765,21102556 Component
3516 GO:0005654 IDA located_in nucleoplasm Component
3516 GO:0005730 IDA located_in nucleolus 9874765 Component
3516 GO:0005737 IDA located_in cytoplasm 21102556 Component
3516 GO:0017053 IDA part_of transcription repressor complex 16691198 Component