Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3630
  • Symbol: INS
  • Description: insulin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3630 GO:0001819 IDA involved_in positive regulation of cytokine production 15473891 Process
3630 GO:0002674 IDA involved_in negative regulation of acute inflammatory response 11443198 Process
3630 GO:0006521 IMP involved_in regulation of cellular amino acid metabolic process 3553851 Process
3630 GO:0006953 IDA involved_in acute-phase response 14739855 Process
3630 GO:0007186 IDA involved_in G protein-coupled receptor signaling pathway 9092559 Process
3630 GO:0008284 IDA involved_in positive regulation of cell population proliferation 7688386,17925406 Process
3630 GO:0008286 IDA involved_in insulin receptor signaling pathway 20455999 Process
3630 GO:0010628 IGI involved_in positive regulation of gene expression 25403480 Process
3630 GO:0010629 IDA acts_upstream_of negative regulation of gene expression 31501273 Process
3630 GO:0010750 IDA involved_in positive regulation of nitric oxide mediated signal transduction 15792832 Process
3630 GO:0010750 IMP involved_in positive regulation of nitric oxide mediated signal transduction 14615391 Process
3630 GO:0014068 IDA involved_in positive regulation of phosphatidylinositol 3-kinase signaling 7688386 Process
3630 GO:0022898 IDA involved_in regulation of transmembrane transporter activity 14615391 Process
3630 GO:0032148 IDA involved_in activation of protein kinase B activity 8702995 Process
3630 GO:0032880 IDA involved_in regulation of protein localization 14615391 Process
3630 GO:0033861 IDA involved_in negative regulation of NAD(P)H oxidase activity 11443198 Process
3630 GO:0038060 IDA involved_in nitric oxide-cGMP-mediated signaling pathway 14744991 Process
3630 GO:0042060 IDA involved_in wound healing 9498508 Process
3630 GO:0042177 IDA involved_in negative regulation of protein catabolic process 15185208 Process
3630 GO:0042311 IDA involved_in vasodilation 14744991 Process
3630 GO:0042593 IMP involved_in glucose homeostasis 381941 Process
3630 GO:0043410 IDA involved_in positive regulation of MAPK cascade 11500939,20455999 Process
3630 GO:0045725 IDA involved_in positive regulation of glycogen biosynthetic process 17925406 Process
3630 GO:0045818 IMP involved_in negative regulation of glycogen catabolic process 381941 Process
3630 GO:0045821 IDA involved_in positive regulation of glycolytic process 7688386 Process
3630 GO:0045821 IMP involved_in positive regulation of glycolytic process 381941 Process
3630 GO:0045840 IDA involved_in positive regulation of mitotic nuclear division 10644978,11500939 Process
3630 GO:0045861 IMP involved_in negative regulation of proteolysis 3553851 Process
3630 GO:0045922 IMP involved_in negative regulation of fatty acid metabolic process 1184755 Process
3630 GO:0046326 IDA involved_in positive regulation of glucose import 14615391,15792832 Process
3630 GO:0046326 IMP involved_in positive regulation of glucose import 14615391 Process
3630 GO:0046628 IDA involved_in positive regulation of insulin receptor signaling pathway 7688386,15792832 Process
3630 GO:0046628 IMP involved_in positive regulation of insulin receptor signaling pathway 14615391 Process
3630 GO:0046631 IDA involved_in alpha-beta T cell activation 10604997 Process
3630 GO:0050708 IDA involved_in regulation of protein secretion 15591776 Process
3630 GO:0050709 IDA involved_in negative regulation of protein secretion 14739855 Process
3630 GO:0050995 IMP involved_in negative regulation of lipid catabolic process 24675707 Process
3630 GO:0051092 IDA involved_in positive regulation of NF-kappaB transcription factor activity 19727662 Process
3630 GO:0051247 IMP involved_in positive regulation of protein metabolic process 3553851 Process
3630 GO:0051897 IDA involved_in positive regulation of protein kinase B signaling 11500939,25240198 Process
3630 GO:0055089 IMP involved_in fatty acid homeostasis 1184755 Process
3630 GO:0060266 IDA involved_in negative regulation of respiratory burst involved in inflammatory response 11443198 Process
3630 GO:0060267 IDA involved_in positive regulation of respiratory burst 9092559 Process
3630 GO:1900182 IDA involved_in positive regulation of protein localization to nucleus 20455999 Process
3630 GO:1902952 IGI involved_in positive regulation of dendritic spine maintenance 19188609 Process
3630 GO:1903076 IGI involved_in regulation of protein localization to plasma membrane 19188609 Process
3630 GO:1903427 IGI involved_in negative regulation of reactive oxygen species biosynthetic process 19188609 Process
3630 GO:1990535 IGI involved_in neuron projection maintenance 19188609 Process
3630 GO:2000252 IDA involved_in negative regulation of feeding behavior 17957153 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3630 GO:0002020 IPI enables protease binding 20082125 Function
3630 GO:0005158 IDA enables insulin receptor binding 7556975,9667398 Function
3630 GO:0005158 IPI enables insulin receptor binding 8452530 Function
3630 GO:0005159 IPI enables insulin-like growth factor receptor binding 8452530 Function
3630 GO:0005179 IMP enables hormone activity 381941 Function
3630 GO:0005515 IPI enables protein binding 9388210,9773776,17051221,23302862,29512653,32296183..... Function
3630 GO:0042802 IPI enables identical protein binding 17472440,20738396,22854022,23106816,23416304,23510797..... Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3630 GO:0005615 IDA located_in extracellular space 9667398 Component