Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 37528
  • Symbol: Fmr1
  • Description: Fragile X messenger ribonucleoprotein 1

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
37528 GO:0000139 IDA located_in Golgi membrane 15621528 Component
37528 GO:0005737 IDA located_in cytoplasm 23874212,28073926 Component
37528 GO:0010494 IDA located_in cytoplasmic stress granule 29212015 Component
37528 GO:0016442 IDA part_of RISC complex 14508492 Component
37528 GO:0016442 IPI part_of RISC complex 12368260 Component
37528 GO:0032838 IDA located_in plasma membrane bounded cell projection cytoplasm 28793261 Component
37528 GO:0043005 IDA located_in neuron projection 28793261 Component
37528 GO:0043025 IDA located_in neuronal cell body 28793261 Component
37528 GO:0043186 IDA located_in P granule 25908854 Component
37528 GO:0071598 IDA located_in neuronal ribonucleoprotein granule 17178403,26385636 Component
37528 GO:1990124 IDA part_of messenger ribonucleoprotein complex 17178403 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
37528 GO:0000900 IDA enables mRNA regulatory element binding translation repressor activity 34531401 Function
37528 GO:0003723 IDA enables RNA binding 12446764,21068064 Function
37528 GO:0003723 IPI enables RNA binding 23666178 Function
37528 GO:0003729 IDA enables mRNA binding 30115809 Function
37528 GO:0005515 IPI enables protein binding 11733059,12368261,12818175,14508492,16949822,18780789,33428246..... Function
37528 GO:0017151 IPI enables DEAD/H-box RNA helicase binding 17178403 Function
37528 GO:0043621 IDA enables protein self-association 12446764 Function
37528 GO:0045182 IMP enables translation regulator activity 11733059 Function
37528 GO:0140693 IDA enables molecular condensate scaffold activity 35165263 Function
37528 GO:1990247 IDA enables N6-methyladenosine-containing RNA binding 33428246,35165263 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
37528 GO:0002052 IMP involved_in positive regulation of neuroblast proliferation 22513101 Process
37528 GO:0006417 IMP involved_in regulation of translation 15737929 Process
37528 GO:0006935 IMP NOT involved_in chemotaxis 12086644 Process
37528 GO:0007268 IMP NOT involved_in chemical synaptic transmission 12086643 Process
37528 GO:0007279 IMP involved_in pole cell formation 16888325,16949822 Process
37528 GO:0007281 IGI involved_in germ cell development 19343200 Process
37528 GO:0007281 IMP involved_in germ cell development 15737929 Process
37528 GO:0007288 IMP involved_in sperm axoneme assembly 15183715 Process
37528 GO:0007294 IMP involved_in germarium-derived oocyte fate determination 15737929 Process
37528 GO:0007310 IGI involved_in oocyte dorsal/ventral axis specification 15737929 Process
37528 GO:0007349 IDA involved_in cellularization 17110444 Process
37528 GO:0007349 IGI involved_in cellularization 21068064 Process
37528 GO:0007409 IMP involved_in axonogenesis 23666178 Process
37528 GO:0007411 IGI involved_in axon guidance 12818175 Process
37528 GO:0007411 IMP involved_in axon guidance 12086643,12818175,23666178 Process
37528 GO:0007413 IMP involved_in axonal fasciculation 15964283 Process
37528 GO:0007420 IMP involved_in brain development 15964283 Process
37528 GO:0007528 IMP involved_in neuromuscular junction development 18354025 Process
37528 GO:0007614 IMP NOT involved_in short-term memory 24344294 Process
37528 GO:0007614 IMP involved_in short-term memory 20463240 Process
37528 GO:0007616 IMP involved_in long-term memory 18776892,20463240,22993428,24344294 Process
37528 GO:0007623 IMP involved_in circadian rhythm 12086643,12086644 Process
37528 GO:0007625 IMP involved_in grooming behavior 22087250 Process
37528 GO:0008049 IMP involved_in male courtship behavior 20463240,22087250 Process
37528 GO:0008306 IMP involved_in associative learning 22993428 Process
37528 GO:0008344 IMP involved_in adult locomotory behavior 22087250 Process
37528 GO:0008345 IMP involved_in larval locomotory behavior 15202995 Process
37528 GO:0008355 IMP involved_in olfactory learning 18776892,22080836 Process
37528 GO:0009794 IGI involved_in regulation of mitotic cell cycle, embryonic 21068064 Process
37528 GO:0010608 IMP involved_in post-transcriptional regulation of gene expression 29212015 Process
37528 GO:0010629 IMP involved_in negative regulation of gene expression 18321984 Process
37528 GO:0016319 IMP involved_in mushroom body development 15215302 Process
37528 GO:0016322 IMP involved_in neuron remodeling 18321984 Process
37528 GO:0017148 IDA involved_in negative regulation of translation 11733059,20442204,34531401 Process
37528 GO:0017148 IEP involved_in negative regulation of translation 11733059 Process
37528 GO:0017148 IMP involved_in negative regulation of translation 23666178,28073926 Process
37528 GO:0030517 IGI involved_in negative regulation of axon extension 33428246 Process
37528 GO:0031047 IMP involved_in regulatory ncRNA-mediated gene silencing 25908854 Process
37528 GO:0031507 IMP involved_in heterochromatin formation 16888325 Process
37528 GO:0035176 IMP involved_in social behavior 20519966 Process
37528 GO:0042048 IMP involved_in olfactory behavior 28366741 Process
37528 GO:0042127 IGI involved_in regulation of cell population proliferation 19306863 Process
37528 GO:0042127 IMP involved_in regulation of cell population proliferation 19306863 Process
37528 GO:0042331 IMP NOT involved_in phototaxis 12086644 Process
37528 GO:0043068 IMP involved_in positive regulation of programmed cell death 21596027 Process
37528 GO:0045448 IMP involved_in mitotic cell cycle, embryonic 16949822 Process
37528 GO:0045475 IMP involved_in locomotor rhythm 12176363,15964283,20463240 Process
37528 GO:0045727 IDA involved_in positive regulation of translation 30115809 Process
37528 GO:0045886 IMP involved_in negative regulation of synaptic assembly at neuromuscular junction 23439121,25908854,32107003 Process
37528 GO:0046627 IGI involved_in negative regulation of insulin receptor signaling pathway 29212015 Process
37528 GO:0046627 IMP involved_in negative regulation of insulin receptor signaling pathway 22513101,27090306,29212015 Process
37528 GO:0046959 IMP involved_in habituation 24344294 Process
37528 GO:0048134 IGI involved_in germ-line cyst formation 19306863 Process
37528 GO:0048134 IMP involved_in germ-line cyst formation 19306863 Process
37528 GO:0048621 IMP involved_in post-embryonic digestive tract morphogenesis 29212015 Process
37528 GO:0048812 IMP involved_in neuron projection morphogenesis 18354025 Process
37528 GO:0048814 IMP involved_in regulation of dendrite morphogenesis 14530299 Process
37528 GO:0050774 IMP involved_in negative regulation of dendrite morphogenesis 15498496,19005053 Process
37528 GO:0050802 IMP involved_in circadian sleep/wake cycle, sleep 19228950 Process
37528 GO:0050807 IGI involved_in regulation of synapse organization 12818175 Process
37528 GO:0050807 IMP involved_in regulation of synapse organization 12818175,15498496 Process
37528 GO:0050808 IMP involved_in synapse organization 21669931 Process
37528 GO:0050976 IMP involved_in detection of mechanical stimulus involved in sensory perception of touch 23666178 Process
37528 GO:0051028 IMP involved_in mRNA transport 18655836 Process
37528 GO:0051823 IMP involved_in regulation of synapse structural plasticity 19738924 Process
37528 GO:0051964 IMP involved_in negative regulation of synapse assembly 15621528,22080836 Process
37528 GO:0061014 IDA involved_in positive regulation of mRNA catabolic process 35165263 Process
37528 GO:0070142 IMP involved_in synaptic vesicle budding 18280750 Process
37528 GO:0072375 IMP involved_in medium-term memory 25921541 Process
37528 GO:0072553 IMP involved_in terminal button organization 28073926 Process
37528 GO:0090328 IMP involved_in regulation of olfactory learning 24344294 Process
37528 GO:0097091 IMP involved_in synaptic vesicle clustering 18280750 Process
37528 GO:0098883 IMP involved_in synapse pruning 18321984 Process
37528 GO:0140694 IDA involved_in non-membrane-bounded organelle assembly 35165263 Process
37528 GO:1900073 IMP involved_in regulation of neuromuscular synaptic transmission 24046358 Process
37528 GO:1900364 IMP involved_in negative regulation of mRNA polyadenylation 28793261 Process
37528 GO:1990834 IMP involved_in response to odorant 28366741 Process
37528 GO:2000647 IMP involved_in negative regulation of stem cell proliferation 29212015 Process