Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3757
  • Symbol: KCNH2
  • Description: potassium voltage-gated channel subfamily H member 2

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3757 GO:0000976 IDA enables transcription cis-regulatory region binding 31146003 Function
3757 GO:0005242 IDA enables inward rectifier potassium channel activity 7604285,8587608 Function
3757 GO:0005242 IMP enables inward rectifier potassium channel activity 14525949 Function
3757 GO:0005249 IDA enables voltage-gated potassium channel activity 11953308,21063088,28280240 Function
3757 GO:0005251 IDA enables delayed rectifier potassium channel activity 7736582 Function
3757 GO:0005251 IGI enables delayed rectifier potassium channel activity 25281747 Function
3757 GO:0005515 IPI enables protein binding 11953308,16361248,18923542 Function
3757 GO:0031625 IPI enables ubiquitin protein ligase binding 21463633 Function
3757 GO:0042802 IPI enables identical protein binding 8995352,24931372 Function
3757 GO:0042803 IPI enables protein homodimerization activity 8995352 Function
3757 GO:0055131 IPI enables C3HC4-type RING finger domain binding 25281747 Function
3757 GO:0097110 IPI enables scaffold protein binding 18923542 Function
3757 GO:1902282 IMP enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 21536673 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3757 GO:0005886 IDA located_in plasma membrane 21463633 Component
3757 GO:0005886 IMP located_in plasma membrane 25281747 Component
3757 GO:0008076 IDA part_of voltage-gated potassium channel complex 7604285,7736582,8587608 Component
3757 GO:0008076 IMP part_of voltage-gated potassium channel complex 25281747 Component
3757 GO:0009986 IDA located_in cell surface 21536673 Component
3757 GO:0048471 IMP located_in perinuclear region of cytoplasm 25281747 Component
3757 GO:1902937 IMP part_of inward rectifier potassium channel complex 14525949 Component

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3757 GO:0042391 IDA involved_in regulation of membrane potential 8587608,21463633 Process
3757 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 31146003 Process
3757 GO:0055075 IDA involved_in potassium ion homeostasis 7604285,8587608 Process
3757 GO:0060048 IMP involved_in cardiac muscle contraction 21536673 Process
3757 GO:0060306 IDA involved_in regulation of membrane repolarization 7736582,21463633 Process
3757 GO:0060307 IMP involved_in regulation of ventricular cardiac muscle cell membrane repolarization 21536673 Process
3757 GO:0071466 IDA involved_in cellular response to xenobiotic stimulus 7604285 Process
3757 GO:0071805 IDA involved_in potassium ion transmembrane transport 7604285,7736582,8587608,11953308,21063088 Process
3757 GO:0086005 IMP involved_in ventricular cardiac muscle cell action potential 21536673 Process
3757 GO:0086009 IMP involved_in membrane repolarization 14525949 Process
3757 GO:0086010 IDA involved_in membrane depolarization during action potential 7604285 Process
3757 GO:0086011 IDA involved_in membrane repolarization during action potential 7736582,11953308,21463633 Process
3757 GO:0086013 IMP involved_in membrane repolarization during cardiac muscle cell action potential 21536673 Process
3757 GO:0086091 IMP acts_upstream_of_or_within regulation of heart rate by cardiac conduction 7889573 Process
3757 GO:0086091 IMP involved_in regulation of heart rate by cardiac conduction 21536673 Process
3757 GO:0097623 IDA involved_in potassium ion export across plasma membrane 7604285 Process
3757 GO:0097623 IGI involved_in potassium ion export across plasma membrane 25281747 Process
3757 GO:0098915 IMP involved_in membrane repolarization during ventricular cardiac muscle cell action potential 21536673 Process
3757 GO:1901379 IDA involved_in regulation of potassium ion transmembrane transport 11953308 Process
3757 GO:1901380 IDA involved_in negative regulation of potassium ion transmembrane transport 7604285,8587608 Process
3757 GO:1901381 IDA involved_in positive regulation of potassium ion transmembrane transport 7736582 Process
3757 GO:1903765 IDA involved_in negative regulation of potassium ion export across plasma membrane 7604285,8587608 Process
3757 GO:1990573 IDA involved_in potassium ion import across plasma membrane 7604285 Process