Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3952
  • Symbol: LEP
  • Description: leptin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3952 GO:0001525 IDA involved_in angiogenesis 19910644,21771332 Process
3952 GO:0001890 IDA involved_in placenta development 17957153 Process
3952 GO:0001934 IDA involved_in positive regulation of protein phosphorylation 27037668 Process
3952 GO:0001936 IDA involved_in regulation of endothelial cell proliferation 11460888 Process
3952 GO:0010507 IDA involved_in negative regulation of autophagy 25060689 Process
3952 GO:0014068 IDA involved_in positive regulation of phosphatidylinositol 3-kinase signaling 24340098 Process
3952 GO:0019953 IMP involved_in sexual reproduction 8589726 Process
3952 GO:0032008 IDA involved_in positive regulation of TOR signaling 25060689 Process
3952 GO:0032310 IDA involved_in prostaglandin secretion 19688109 Process
3952 GO:0032755 IDA involved_in positive regulation of interleukin-6 production 19688109 Process
3952 GO:0032757 IDA involved_in positive regulation of interleukin-8 production 19688109 Process
3952 GO:0032814 IDA involved_in regulation of natural killer cell activation 12504075 Process
3952 GO:0032817 IDA involved_in regulation of natural killer cell proliferation 12504075 Process
3952 GO:0042102 IDA involved_in positive regulation of T cell proliferation 25060689 Process
3952 GO:0042269 IDA involved_in regulation of natural killer cell mediated cytotoxicity 12504075 Process
3952 GO:0043410 IDA involved_in positive regulation of MAPK cascade 24340098 Process
3952 GO:0044320 IDA involved_in cellular response to leptin stimulus 17344214 Process
3952 GO:0045765 IDA involved_in regulation of angiogenesis 11460888 Process
3952 GO:0046325 IDA involved_in negative regulation of glucose import 24340098 Process
3952 GO:0046427 IDA involved_in positive regulation of receptor signaling pathway via JAK-STAT 17344214 Process
3952 GO:0048639 IDA involved_in positive regulation of developmental growth 17957153 Process
3952 GO:0050892 IDA involved_in intestinal absorption 24340098 Process
3952 GO:0050999 IDA involved_in regulation of nitric-oxide synthase activity 15899045 Process
3952 GO:0051726 IDA involved_in regulation of cell cycle 17344214 Process
3952 GO:1900015 IDA involved_in regulation of cytokine production involved in inflammatory response 19688109 Process
3952 GO:1900745 IDA involved_in positive regulation of p38MAPK cascade 24340098 Process
3952 GO:1990051 IDA involved_in activation of protein kinase C activity 24340098 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
3952 GO:0005515 IPI enables protein binding 32296183 Function
3952 GO:1990460 IDA enables leptin receptor binding 27037668 Function