Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 40201
• Symbol: gig
• Description: gigas

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40201	GO:0001934	IDA	involved_in	positive regulation of protein phosphorylation	23393158	Process
40201	GO:0007165	IGI	involved_in	signal transduction	12172555	Process
40201	GO:0007584	IMP	involved_in	response to nutrient	12172555	Process
40201	GO:0008285	IGI	involved_in	negative regulation of cell population proliferation	11348591	Process
40201	GO:0008285	IMP	involved_in	negative regulation of cell population proliferation	12172554	Process
40201	GO:0008340	IMP	involved_in	determination of adult lifespan	15186745	Process
40201	GO:0010508	IGI	involved_in	positive regulation of autophagy	29606597	Process
40201	GO:0010508	IMP	involved_in	positive regulation of autophagy	18474623	Process
40201	GO:0030308	IGI	involved_in	negative regulation of cell growth	11348591,12172554	Process
40201	GO:0030308	IMP	involved_in	negative regulation of cell growth	11348591,12172555	Process
40201	GO:0030948	IMP	involved_in	negative regulation of vascular endothelial growth factor receptor signaling pathway	23878397	Process
40201	GO:0032007	IGI	involved_in	negative regulation of TOR signaling	12172555	Process
40201	GO:0035069	IGI	involved_in	larval midgut histolysis	22555456	Process
40201	GO:0042325	IDA	involved_in	regulation of phosphorylation	20585550	Process
40201	GO:0042632	IGI	involved_in	cholesterol homeostasis	27326933	Process
40201	GO:0045792	IGI	involved_in	negative regulation of cell size	11348592,11390358	Process
40201	GO:0045792	IMP	involved_in	negative regulation of cell size	12766776,19216764,19917724	Process
40201	GO:0045886	IMP	involved_in	negative regulation of synaptic assembly at neuromuscular junction	23393158	Process
40201	GO:0046621	IGI	involved_in	negative regulation of organ growth	11348592,11390358	Process
40201	GO:0046627	IGI	involved_in	negative regulation of insulin receptor signaling pathway	11348592,11390358	Process
40201	GO:0048477	IMP	involved_in	oogenesis	10052455,24531791	Process
40201	GO:0048542	IMP	involved_in	lymph gland development	22510984	Process
40201	GO:0051726	IMP	involved_in	regulation of cell cycle	10052455,11348591	Process
40201	GO:0055088	IGI	involved_in	lipid homeostasis	17136098	Process
40201	GO:0071456	IMP	involved_in	cellular response to hypoxia	18653470	Process
40201	GO:1902350	IMP	involved_in	cellular response to chloroquine	24265594	Process
40201	GO:1904262	IGI	involved_in	negative regulation of TORC1 signaling	22493059,28829944	Process
40201	GO:1904262	IMP	involved_in	negative regulation of TORC1 signaling	16627617,23878397,25826530	Process
40201	GO:1904504	IMP	involved_in	positive regulation of lipophagy	29503179	Process
40201	GO:1904515	IGI	involved_in	positive regulation of TORC2 signaling	22493059	Process
40201	GO:1904515	IMP	involved_in	positive regulation of TORC2 signaling	16627617	Process
40201	GO:2000331	IMP	involved_in	regulation of terminal button organization	25361581	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40201	GO:0005096	IDA	enables	GTPase activator activity	12771962	Function
40201	GO:0005515	IPI	enables	protein binding	11348592,18381890	Function
40201	GO:0019900	IPI	enables	kinase binding	12172555	Function
40201	GO:0019901	IPI	enables	protein kinase binding	12172555	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40201	GO:0005737	IDA	located_in	cytoplasm	12172554	Component
40201	GO:0005829	IDA	located_in	cytosol	29144896	Component
40201	GO:0033596	IDA	part_of	TSC1-TSC2 complex	11390358,12172554	Component
40201	GO:0033596	IPI	part_of	TSC1-TSC2 complex	12771962	Component