Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 40248
• Symbol: Ide
• Description: Insulin degrading metalloproteinase

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40248	GO:0005737	IDA	located_in	cytoplasm	24430872	Component
40248	GO:0005886	IDA	located_in	plasma membrane	24430872	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40248	GO:0006508	IDA	involved_in	proteolysis	2126597,2659071	Process
40248	GO:0008340	IMP	involved_in	determination of adult lifespan	20493190,21212741	Process
40248	GO:0045089	HMP	involved_in	positive regulation of innate immune response	19520911	Process
40248	GO:0045926	IMP	involved_in	negative regulation of growth	20493190	Process
40248	GO:0046627	IGI	involved_in	negative regulation of insulin receptor signaling pathway	24430872	Process
40248	GO:0046662	IMP	involved_in	regulation of egg-laying behavior	21212741	Process
40248	GO:0048640	IMP	involved_in	negative regulation of developmental growth	24430872	Process
40248	GO:0050829	HMP	involved_in	defense response to Gram-negative bacterium	19520911	Process
40248	GO:0090062	IDA	involved_in	regulation of trehalose metabolic process	21212741	Process
40248	GO:1901143	IDA	involved_in	insulin catabolic process	2126597,2659071,3139025	Process
40248	GO:1901143	IMP	involved_in	insulin catabolic process	24430872	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40248	GO:0008237	IDA	enables	metallopeptidase activity	2126597,2659071,3139025	Function