Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 40260
• Symbol: Psn
• Description: Presenilin

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40260	GO:0002027	IMP	involved_in	regulation of heart rate	21524270	Process
40260	GO:0006508	IDA	involved_in	proteolysis	15611340	Process
40260	GO:0006509	IDA	involved_in	membrane protein ectodomain proteolysis	20421416	Process
40260	GO:0006915	IMP	involved_in	apoptotic process	10491396	Process
40260	GO:0007219	IDA	involved_in	Notch signaling pathway	15611340	Process
40260	GO:0007219	IGI	involved_in	Notch signaling pathway	11134525,20421416,28960177	Process
40260	GO:0007219	IMP	involved_in	Notch signaling pathway	10206646,11782315,11782316,12110170,16713961	Process
40260	GO:0007220	IMP	involved_in	Notch receptor processing	10491396,11782315,11782316	Process
40260	GO:0007614	IMP	involved_in	short-term memory	20631179	Process
40260	GO:0008306	IMP	involved_in	associative learning	20631179	Process
40260	GO:0008593	IMP	involved_in	regulation of Notch signaling pathway	21822800	Process
40260	GO:0015677	IMP	involved_in	copper ion import	23667524	Process
40260	GO:0034205	IDA	involved_in	amyloid-beta formation	20421416	Process
40260	GO:0034205	IMP	involved_in	amyloid-beta formation	12110170	Process
40260	GO:0035333	IDA	involved_in	Notch receptor processing, ligand-dependent	15611340	Process
40260	GO:0035333	IGI	involved_in	Notch receptor processing, ligand-dependent	20421416	Process
40260	GO:0048190	IMP	involved_in	wing disc dorsal/ventral pattern formation	16307735	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40260	GO:0004175	IDA	enables	endopeptidase activity	11030342,15611340,28495961	Function
40260	GO:0004175	IMP	enables	endopeptidase activity	15105831,20421416	Function
40260	GO:0005515	IPI	enables	protein binding	23609534	Function
40260	GO:0042803	IPI	enables	protein homodimerization activity	11557046	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
40260	GO:0005770	IDA	located_in	late endosome	20421416	Component
40260	GO:0005886	IDA	located_in	plasma membrane	10662508	Component
40260	GO:0016324	IDA	located_in	apical plasma membrane	11781576	Component
40260	GO:0055037	IDA	located_in	recycling endosome	20421416	Component
40260	GO:0070765	IDA	part_of	gamma-secretase complex	12660785	Component
40260	GO:0070765	IPI	part_of	gamma-secretase complex	20421416	Component