Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 40336
  • Symbol: park
  • Description: parkin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
40336 GO:0000209 IDA involved_in protein polyubiquitination 17456438 Process
40336 GO:0000209 IMP involved_in protein polyubiquitination 32047033 Process
40336 GO:0000266 IGI involved_in mitochondrial fission 18230723 Process
40336 GO:0000422 IMP involved_in autophagy of mitochondrion 20194754,24192653 Process
40336 GO:0006511 IMP involved_in ubiquitin-dependent protein catabolic process 20194754 Process
40336 GO:0006513 IDA involved_in protein monoubiquitination 29689197 Process
40336 GO:0006513 IMP involved_in protein monoubiquitination 32047033 Process
40336 GO:0006979 IMP involved_in response to oxidative stress 15911761,21383066 Process
40336 GO:0007005 IMP involved_in mitochondrion organization 12642658,17123504,17687034,18230723,18443288,24852371,29456190..... Process
40336 GO:0007283 IMP involved_in spermatogenesis 17123504,21383066 Process
40336 GO:0008344 IMP involved_in adult locomotory behavior 17687034,24852371 Process
40336 GO:0008345 IMP involved_in larval locomotory behavior 27430166 Process
40336 GO:0010637 IGI involved_in negative regulation of mitochondrial fusion 18799731 Process
40336 GO:0010637 IMP involved_in negative regulation of mitochondrial fusion 20194754 Process
40336 GO:0010821 IMP involved_in regulation of mitochondrion organization 19546216 Process
40336 GO:0016567 IDA involved_in protein ubiquitination 17456438 Process
40336 GO:0016567 IMP involved_in protein ubiquitination 24898855,24901221 Process
40336 GO:0030382 IMP involved_in sperm mitochondrion organization 12642658,18799731 Process
40336 GO:0046329 IDA involved_in negative regulation of JNK cascade 16002472 Process
40336 GO:0046329 IGI involved_in negative regulation of JNK cascade 20496123 Process
40336 GO:0048078 IMP involved_in positive regulation of compound eye pigmentation 19692353 Process
40336 GO:0048477 IMP involved_in oogenesis 20869429,21383066 Process
40336 GO:0051865 IDA involved_in protein autoubiquitination 17456438 Process
40336 GO:0061734 IMP involved_in parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization 24192653 Process
40336 GO:0070050 IMP involved_in neuron cellular homeostasis 17687034 Process
40336 GO:0090141 IMP involved_in positive regulation of mitochondrial fission 18799731,20194754 Process
40336 GO:1900407 IDA involved_in regulation of cellular response to oxidative stress 20483372 Process
40336 GO:1901526 IMP involved_in positive regulation of mitophagy 28435104 Process
40336 GO:1903599 IGI involved_in positive regulation of autophagy of mitochondrion 27906179 Process
40336 GO:1903599 IMP involved_in positive regulation of autophagy of mitochondrion 23509287 Process
40336 GO:1904061 IMP involved_in positive regulation of locomotor rhythm 28435104 Process
40336 GO:1904457 IMP involved_in positive regulation of neuronal action potential 28435104 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
40336 GO:0004842 IDA enables ubiquitin-protein transferase activity 17456438 Function
40336 GO:0005515 IPI enables protein binding 32138754 Function
40336 GO:0031624 IPI enables ubiquitin conjugating enzyme binding 17456438 Function
40336 GO:0061630 IDA enables ubiquitin protein ligase activity 17456438,32138754 Function
40336 GO:0061630 IMP enables ubiquitin protein ligase activity 16002472,24901221 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
40336 GO:0005737 IDA located_in cytoplasm 16002472,20194754,20869429 Component
40336 GO:0005739 IDA colocalizes_with mitochondrion 20194754 Component
40336 GO:0005739 IDA located_in mitochondrion 18957282,27906179 Component