Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 406884
  • Symbol: MIRLET7B
  • Description: microRNA let-7b

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
406884 GO:0005615 HDA located_in extracellular space 18766170,26646931 Component
406884 GO:0070062 IDA located_in extracellular exosome 28159509,31926946 Component
406884 GO:1903561 HDA located_in extracellular vesicle 28798470 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
406884 GO:0010507 IDA involved_in negative regulation of autophagy 26296645 Process
406884 GO:0034614 IDA involved_in cellular response to reactive oxygen species 26296645 Process
406884 GO:0035195 IDA involved_in miRNA-mediated gene silencing 15131085,26296645,27809873,28159509 Process
406884 GO:0035279 IDA involved_in miRNA-mediated gene silencing by mRNA destabilization 29471394 Process
406884 GO:0043154 IDA involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 26296645 Process
406884 GO:0045766 IDA involved_in positive regulation of angiogenesis 26296645,28159509 Process
406884 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 26296645 Process
406884 GO:0140367 IDA involved_in antibacterial innate immune response 29471394 Process
406884 GO:1901299 IDA involved_in negative regulation of hydrogen peroxide-mediated programmed cell death 26296645 Process
406884 GO:1903589 IDA involved_in positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 28159509 Process
406884 GO:2000110 IDA involved_in negative regulation of macrophage apoptotic process 29471394 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
406884 GO:1903231 IDA enables mRNA base-pairing translational repressor activity 15131085,26296645,27809873,29471394 Function