Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 4204
  • Symbol: MECP2
  • Description: methyl-CpG binding protein 2

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4204 GO:0000792 IDA part_of heterochromatin 11441023 Component
4204 GO:0005615 HDA located_in extracellular space 22664934 Component
4204 GO:0005634 IDA located_in nucleus 11441023,21782149 Component
4204 GO:0005654 IDA located_in nucleoplasm Component
4204 GO:0005813 IMP located_in centrosome 25527496 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4204 GO:0003676 EXP enables nucleic acid binding 20405910 Function
4204 GO:0003714 IDA enables transcription corepressor activity 10773092 Function
4204 GO:0003723 HDA enables RNA binding 22658674 Function
4204 GO:0005515 IPI enables protein binding 11441023,15696166,19820693,23770565,25609649,28348241,29636529..... Function
4204 GO:0010385 IMP enables double-stranded methylated DNA binding 17296936 Function
4204 GO:0060090 EXP enables molecular adaptor activity 20405910 Function
4204 GO:0140693 IMP enables molecular condensate scaffold activity 32698189 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4204 GO:0006349 IMP acts_upstream_of_or_within regulation of gene expression by genomic imprinting 15608638 Process
4204 GO:0007052 IMP involved_in mitotic spindle organization 25527496 Process
4204 GO:0008284 IMP involved_in positive regulation of cell population proliferation 25527496 Process
4204 GO:0010629 IDA involved_in negative regulation of gene expression 23960241 Process
4204 GO:0010971 IMP involved_in positive regulation of G2/M transition of mitotic cell cycle 25527496 Process
4204 GO:0016525 IMP involved_in negative regulation of angiogenesis 23960241 Process
4204 GO:0043537 IDA involved_in negative regulation of blood vessel endothelial cell migration 23960241 Process
4204 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 11441023 Process
4204 GO:0090063 IMP involved_in positive regulation of microtubule nucleation 25527496 Process
4204 GO:1905643 IDA involved_in positive regulation of DNA methylation 23960241 Process