Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 4208
  • Symbol: MEF2C
  • Description: myocyte enhancer factor 2C

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4208 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 18079734 Process
4208 GO:0000165 IDA involved_in MAPK cascade 9858528 Process
4208 GO:0000165 IMP involved_in MAPK cascade 11160896 Process
4208 GO:0006355 IDA involved_in regulation of DNA-templated transcription 24008018 Process
4208 GO:0007507 IEP involved_in heart development 10458488 Process
4208 GO:0010628 IDA involved_in positive regulation of gene expression 9857019,21556048 Process
4208 GO:0014902 IEP involved_in myotube differentiation 8455629 Process
4208 GO:0030182 IEP involved_in neuron differentiation 8455629 Process
4208 GO:0030279 IDA involved_in negative regulation of ossification 17696759 Process
4208 GO:0043537 IGI involved_in negative regulation of blood vessel endothelial cell migration 26184978 Process
4208 GO:0045663 IMP involved_in positive regulation of myoblast differentiation 9770491 Process
4208 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 17696759 Process
4208 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 8455629,15486975,16043483 Process
4208 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 11160896,21556048 Process
4208 GO:0048643 IMP involved_in positive regulation of skeletal muscle tissue development 9770491 Process
4208 GO:0071374 IDA involved_in cellular response to parathyroid hormone stimulus 17696759 Process
4208 GO:0071560 IDA involved_in cellular response to transforming growth factor beta stimulus 9770491 Process
4208 GO:1904706 IDA involved_in negative regulation of vascular associated smooth muscle cell proliferation 28799067 Process
4208 GO:1904706 IGI involved_in negative regulation of vascular associated smooth muscle cell proliferation 26184978 Process
4208 GO:1904753 IDA involved_in negative regulation of vascular associated smooth muscle cell migration 28799067 Process
4208 GO:1904753 IGI involved_in negative regulation of vascular associated smooth muscle cell migration 26184978 Process
4208 GO:1905563 IGI involved_in negative regulation of vascular endothelial cell proliferation 26184978 Process
4208 GO:2000727 IDA involved_in positive regulation of cardiac muscle cell differentiation 9857019 Process
4208 GO:2001016 IDA involved_in positive regulation of skeletal muscle cell differentiation 21556048 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4208 GO:0000977 IDA enables RNA polymerase II transcription regulatory region sequence-specific DNA binding 8455629 Function
4208 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 8455629 Function
4208 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 15486975 Function
4208 GO:0003680 IDA enables minor groove of adenine-thymine-rich DNA binding 15486975 Function
4208 GO:0003700 IDA enables DNA-binding transcription factor activity 16043483 Function
4208 GO:0005515 IPI enables protein binding 15486975,16510869,18588859,20211142,20936779,21556048,23752268..... Function
4208 GO:0046982 IPI enables protein heterodimerization activity 9858528 Function
4208 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 16043483 Function
4208 GO:0140297 IPI enables DNA-binding transcription factor binding 11160896 Function
4208 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4208 GO:0005634 IDA located_in nucleus 8455629,9770491,16510869,21170291,24008018 Component
4208 GO:0005654 IDA located_in nucleoplasm Component
4208 GO:0005737 IDA located_in cytoplasm 8455629 Component
4208 GO:0016607 IDA located_in nuclear speck 18079734 Component
4208 GO:0032991 IDA part_of protein-containing complex 15486975 Component
4208 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component