Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 42447
• Symbol: Lrrk
• Description: Leucine-rich repeat kinase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
42447	GO:0004672	IDA	enables	protein kinase activity	18701920	Function
42447	GO:0004674	IDA	enables	protein serine/threonine kinase activity	20624856,22998870	Function
42447	GO:0004674	IMP	enables	protein serine/threonine kinase activity	18701920,24916379	Function
42447	GO:0005515	IPI	enables	protein binding	21159966	Function
42447	GO:0031267	IPI	enables	small GTPase binding	22171073,25453831	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
42447	GO:0005737	IDA	located_in	cytoplasm	21159966	Component
42447	GO:0005765	IDA	located_in	lysosomal membrane	22171073	Component
42447	GO:0005795	IDA	located_in	Golgi stack	26216903	Component
42447	GO:0031594	IDA	located_in	neuromuscular junction	21159966	Component
42447	GO:0031902	IDA	located_in	late endosome membrane	22171073	Component
42447	GO:0043195	IDA	located_in	terminal bouton	28482024	Component
42447	GO:0043198	IDA	located_in	dendritic shaft	26216903	Component
42447	GO:0044297	IDA	located_in	cell body	26216903	Component
42447	GO:0061174	IDA	located_in	type I terminal bouton	27720484	Component
42447	GO:0071212	IDA	located_in	subsynaptic reticulum	28482024	Component
42447	GO:1990033	IDA	located_in	dendritic branch point	26216903	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
42447	GO:0006914	IMP	involved_in	autophagy	25288684	Process
42447	GO:0007528	IMP	involved_in	neuromuscular junction development	21159966	Process
42447	GO:0008088	IMP	involved_in	axo-dendritic transport	25316291	Process
42447	GO:0009267	IMP	involved_in	cellular response to starvation	27720484	Process
42447	GO:0018105	IDA	involved_in	peptidyl-serine phosphorylation	22998870	Process
42447	GO:0032418	IGI	involved_in	lysosome localization	22171073	Process
42447	GO:0032418	IMP	involved_in	lysosome localization	22171073	Process
42447	GO:0040011	IMP	involved_in	locomotion	25316291	Process
42447	GO:0042147	IGI	involved_in	retrograde transport, endosome to Golgi	25288684	Process
42447	GO:0043524	IMP	acts_upstream_of	negative regulation of neuron apoptotic process	24916379	Process
42447	GO:0048312	IMP	involved_in	intracellular distribution of mitochondria	21159966	Process
42447	GO:0048488	IGI	involved_in	synaptic vesicle endocytosis	28482024	Process
42447	GO:0050774	IMP	involved_in	negative regulation of dendrite morphogenesis	26216903	Process
42447	GO:0050808	IMP	involved_in	synapse organization	21159966	Process
42447	GO:0051683	IMP	involved_in	establishment of Golgi localization	26216903	Process
42447	GO:0070507	IMP	involved_in	regulation of microtubule cytoskeleton organization	21159966	Process
42447	GO:0090128	IMP	involved_in	regulation of synapse maturation	21159966	Process
42447	GO:1900242	IMP	involved_in	regulation of synaptic vesicle endocytosis	22998870	Process
42447	GO:2000331	IMP	involved_in	regulation of terminal button organization	21159966	Process
42447	GO:2000785	IMP	involved_in	regulation of autophagosome assembly	27720484	Process