Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 42846
  • Symbol: spas
  • Description: spastin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42846 GO:0000070 IMP involved_in mitotic sister chromatid segregation 17452528 Process
42846 GO:0000226 IMP involved_in microtubule cytoskeleton organization 15562320,20457764,27605706 Process
42846 GO:0007026 IDA involved_in negative regulation of microtubule depolymerization 30837315 Process
42846 GO:0007626 IMP involved_in locomotory behavior 15562320 Process
42846 GO:0031117 IDA involved_in positive regulation of microtubule depolymerization 15823537,18202664 Process
42846 GO:0031117 IMP involved_in positive regulation of microtubule depolymerization 15242610,17452528 Process
42846 GO:0035099 IMP involved_in hemocyte migration 20457764 Process
42846 GO:0045834 IMP involved_in positive regulation of lipid metabolic process 25875445 Process
42846 GO:0045886 IMP involved_in negative regulation of synaptic assembly at neuromuscular junction 15562320 Process
42846 GO:0045887 IMP involved_in positive regulation of synaptic assembly at neuromuscular junction 15242610 Process
42846 GO:0048691 IGI involved_in positive regulation of axon extension involved in regeneration 27605706 Process
42846 GO:0050775 IMP involved_in positive regulation of dendrite morphogenesis 21368042 Process
42846 GO:0051013 IDA involved_in microtubule severing 30837315 Process
42846 GO:0051013 IMP involved_in microtubule severing 17452528,18202664 Process
42846 GO:1900074 IMP involved_in negative regulation of neuromuscular synaptic transmission 15242610 Process
42846 GO:1900075 IMP involved_in positive regulation of neuromuscular synaptic transmission 15562320 Process
42846 GO:2000331 IMP involved_in regulation of terminal button organization 15562320 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42846 GO:0005515 IPI enables protein binding 19341724 Function
42846 GO:0008017 IDA enables microtubule binding 30837315 Function
42846 GO:0008017 IMP enables microtubule binding 18202664 Function
42846 GO:0008568 IDA enables microtubule severing ATPase activity 15823537,30837315 Function
42846 GO:0008568 IMP enables microtubule severing ATPase activity 17452528,18202664 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42846 GO:0005694 IDA located_in chromosome 17452528 Component
42846 GO:0005737 IDA located_in cytoplasm 15242610,15562320,15823537 Component
42846 GO:0005813 IDA located_in centrosome 17452528 Component
42846 GO:0008021 IDA colocalizes_with synaptic vesicle 15242610 Component
42846 GO:0015630 IDA located_in microtubule cytoskeleton 18202664 Component
42846 GO:0031594 IDA located_in neuromuscular junction 15242610 Component
42846 GO:0043195 IDA located_in terminal bouton 15242610 Component