Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 42862
  • Symbol: Tsc1
  • Description: Tsc1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42862 GO:0005096 IDA enables GTPase activator activity 12771962 Function
42862 GO:0005515 IPI enables protein binding 16054033,29187524 Function
42862 GO:0019900 IPI enables kinase binding 12172555 Function
42862 GO:0019901 IPI enables protein kinase binding 12172555 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42862 GO:0005737 IDA located_in cytoplasm 12172554 Component
42862 GO:0033596 IDA part_of TSC1-TSC2 complex 11390358,12172554 Component
42862 GO:0033596 IPI part_of TSC1-TSC2 complex 11348592,12771962 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42862 GO:0007165 IGI involved_in signal transduction 12172555 Process
42862 GO:0007424 HMP involved_in open tracheal system development 21750678 Process
42862 GO:0007584 IMP involved_in response to nutrient 12172555 Process
42862 GO:0008285 IGI involved_in negative regulation of cell population proliferation 11348591 Process
42862 GO:0008285 IMP involved_in negative regulation of cell population proliferation 12172554 Process
42862 GO:0008340 IMP involved_in determination of adult lifespan 15186745 Process
42862 GO:0010508 IGI involved_in positive regulation of autophagy 29606597 Process
42862 GO:0010508 IMP involved_in positive regulation of autophagy 18474623 Process
42862 GO:0030308 IGI involved_in negative regulation of cell growth 11348591,12172554 Process
42862 GO:0030308 IMP involved_in negative regulation of cell growth 11348591,12172555 Process
42862 GO:0030948 IMP involved_in negative regulation of vascular endothelial growth factor receptor signaling pathway 23878397 Process
42862 GO:0032007 IGI involved_in negative regulation of TOR signaling 12172555 Process
42862 GO:0035069 IGI involved_in larval midgut histolysis 22555456 Process
42862 GO:0035332 IMP involved_in positive regulation of hippo signaling 26474042 Process
42862 GO:0035883 IMP involved_in enteroendocrine cell differentiation 23843608 Process
42862 GO:0036335 IMP involved_in intestinal stem cell homeostasis 23843608 Process
42862 GO:0042127 IMP involved_in regulation of cell population proliferation 20808898 Process
42862 GO:0042325 IDA involved_in regulation of phosphorylation 20585550 Process
42862 GO:0042632 IGI involved_in cholesterol homeostasis 27326933 Process
42862 GO:0045571 IMP involved_in negative regulation of imaginal disc growth 29719260 Process
42862 GO:0045792 IGI involved_in negative regulation of cell size 11348592,11390358 Process
42862 GO:0045792 IMP involved_in negative regulation of cell size 11390358,12766776,19216764,19917724 Process
42862 GO:0046621 IGI involved_in negative regulation of organ growth 11348592,11390358 Process
42862 GO:0046621 IMP involved_in negative regulation of organ growth 11348591,11390358 Process
42862 GO:0046627 IGI involved_in negative regulation of insulin receptor signaling pathway 11348592,11390358 Process
42862 GO:0046627 IMP involved_in negative regulation of insulin receptor signaling pathway 14645523 Process
42862 GO:0048477 IGI involved_in oogenesis 24786828 Process
42862 GO:0048505 IMP involved_in regulation of timing of cell differentiation 15454083 Process
42862 GO:0048542 IMP involved_in lymph gland development 22510984 Process
42862 GO:0048640 IMP involved_in negative regulation of developmental growth 18177722 Process
42862 GO:0051726 IMP involved_in regulation of cell cycle 11348591 Process
42862 GO:0055088 IGI involved_in lipid homeostasis 17136098 Process
42862 GO:0071456 IMP involved_in cellular response to hypoxia 18653470 Process
42862 GO:1902350 IMP involved_in cellular response to chloroquine 24265594 Process
42862 GO:1904262 IGI involved_in negative regulation of TORC1 signaling 22493059,28829944 Process
42862 GO:1904262 IMP involved_in negative regulation of TORC1 signaling 16627617,23878397 Process
42862 GO:1904515 IGI involved_in positive regulation of TORC2 signaling 22493059 Process
42862 GO:1904515 IMP involved_in positive regulation of TORC2 signaling 16627617 Process
42862 GO:2000331 IMP involved_in regulation of terminal button organization 25361581 Process