Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 42896
  • Symbol: crb
  • Description: crumbs

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42896 GO:0001745 IGI involved_in compound eye morphogenesis 20498073 Process
42896 GO:0001745 IMP involved_in compound eye morphogenesis 20498073 Process
42896 GO:0003383 IMP involved_in apical constriction 28263180 Process
42896 GO:0007163 IMP involved_in establishment or maintenance of cell polarity 2344615,29084199 Process
42896 GO:0007391 IMP involved_in dorsal closure 26544546 Process
42896 GO:0007399 IMP involved_in nervous system development 17376868 Process
42896 GO:0007424 IMP involved_in open tracheal system development 17113384,30645584 Process
42896 GO:0007435 IMP involved_in salivary gland morphogenesis 12526813,28263180 Process
42896 GO:0007443 IMP involved_in Malpighian tubule morphogenesis 19567473 Process
42896 GO:0008284 IMP involved_in positive regulation of cell population proliferation 16258546 Process
42896 GO:0016332 IMP involved_in establishment or maintenance of polarity of embryonic epithelium 11740559 Process
42896 GO:0016334 IMP involved_in establishment or maintenance of polarity of follicular epithelium 11076972 Process
42896 GO:0032435 IGI involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process 22105348 Process
42896 GO:0032880 IMP involved_in regulation of protein localization 22105348 Process
42896 GO:0033157 IMP involved_in regulation of intracellular protein transport 22105348 Process
42896 GO:0034332 IMP involved_in adherens junction organization 14631116,26644515 Process
42896 GO:0035002 IGI involved_in liquid clearance, open tracheal system 21945316 Process
42896 GO:0035088 IMP involved_in establishment or maintenance of apical/basal cell polarity 16258546 Process
42896 GO:0035090 IMP involved_in maintenance of apical/basal cell polarity 19567473 Process
42896 GO:0035239 IMP involved_in tube morphogenesis 12526813 Process
42896 GO:0035332 IGI involved_in positive regulation of hippo signaling 20498073,25712476 Process
42896 GO:0035332 IMP involved_in positive regulation of hippo signaling 20362445,20798049,26821647,28292426,29440303 Process
42896 GO:0042051 IMP involved_in compound eye photoreceptor development 14631116 Process
42896 GO:0042052 IMP involved_in rhabdomere development 11222137,14631116 Process
42896 GO:0045176 IMP involved_in apical protein localization 19531584,24778256 Process
42896 GO:0045176 IPI involved_in apical protein localization 20498073 Process
42896 GO:0045186 IMP involved_in zonula adherens assembly 11850624 Process
42896 GO:0045218 IMP involved_in zonula adherens maintenance 11850625,15479740,19567473 Process
42896 GO:0045494 IMP involved_in photoreceptor cell maintenance 12361571,22105348 Process
42896 GO:0045570 IMP involved_in regulation of imaginal disc growth 20110329 Process
42896 GO:0045746 IGI involved_in negative regulation of Notch signaling pathway 16440003 Process
42896 GO:0046621 IMP involved_in negative regulation of organ growth 20498073 Process
42896 GO:0046664 IMP involved_in dorsal closure, amnioserosa morphology change 11973353 Process
42896 GO:0046665 IMP involved_in amnioserosa maintenance 26544546 Process
42896 GO:0048190 IMP involved_in wing disc dorsal/ventral pattern formation 16440003 Process
42896 GO:0050821 IMP involved_in protein stabilization 22105348 Process
42896 GO:0051642 IMP involved_in centrosome localization 26644515 Process
42896 GO:0060438 IGI involved_in trachea development 30645584 Process
42896 GO:0061024 IMP involved_in membrane organization 12526813 Process
42896 GO:0061336 IMP involved_in cell morphogenesis involved in Malpighian tubule morphogenesis 19567473 Process
42896 GO:0061541 IMP involved_in rhabdomere morphogenesis 19717208,22608020 Process
42896 GO:0098813 IMP involved_in nuclear chromosome segregation 25065591 Process
42896 GO:0106036 IMP involved_in assembly of apicomedial cortex actomyosin 28263180 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42896 GO:0005080 IPI enables protein kinase C binding 15302858 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
42896 GO:0005634 HDA located_in nucleus 26896675 Component
42896 GO:0005886 HDA located_in plasma membrane 26896675 Component
42896 GO:0005886 IDA located_in plasma membrane 11076972,28515229 Component
42896 GO:0016028 IDA located_in rhabdomere 19834743,22105348,32579558 Component
42896 GO:0016324 IDA located_in apical plasma membrane 20498073,22105348,22658591,28306104,30645584,32579558..... Component
42896 GO:0016327 IDA located_in apicolateral plasma membrane 11740560,15302858 Component
42896 GO:0016327 IPI located_in apicolateral plasma membrane 11740560 Component
42896 GO:0032391 IDA located_in photoreceptor connecting cilium 32579558 Component