Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 42964
• Symbol: Nct
• Description: Nicastrin

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
42964	GO:0005770	IDA	located_in	late endosome	20421416	Component
42964	GO:0005886	HDA	located_in	plasma membrane	19317464	Component
42964	GO:0055037	IDA	located_in	recycling endosome	20421416	Component
42964	GO:0070765	IDA	part_of	gamma-secretase complex	12660785	Component
42964	GO:0070765	IPI	part_of	gamma-secretase complex	20421416	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
42964	GO:0006509	IDA	involved_in	membrane protein ectodomain proteolysis	20421416	Process
42964	GO:0006509	IMP	involved_in	membrane protein ectodomain proteolysis	11781576	Process
42964	GO:0007219	IGI	involved_in	Notch signaling pathway	20421416	Process
42964	GO:0007219	IMP	involved_in	Notch signaling pathway	11781576,11782315,11782316,12110170,16145661,29195077.....	Process
42964	GO:0007220	IGI	involved_in	Notch receptor processing	11781576	Process
42964	GO:0007220	IMP	involved_in	Notch receptor processing	11781576,11782315,11782316	Process
42964	GO:0034205	IDA	involved_in	amyloid-beta formation	20421416	Process
42964	GO:0034205	IMP	involved_in	amyloid-beta formation	12110170	Process
42964	GO:0035333	IGI	involved_in	Notch receptor processing, ligand-dependent	20421416	Process
42964	GO:0045314	IMP	involved_in	regulation of compound eye photoreceptor development	16145661	Process
42964	GO:0046331	IMP	involved_in	lateral inhibition	11782315,16145661	Process