Gene Ontology

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 43991
  • Symbol: Pten
  • Description: Phosphatase and tensin homolog

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
43991 GO:0002164 IMP involved_in larval development 16182527 Process
43991 GO:0006469 IDA involved_in negative regulation of protein kinase activity 10962553 Process
43991 GO:0006914 IMP involved_in autophagy 15296715 Process
43991 GO:0007010 IMP involved_in cytoskeleton organization 10617573 Process
43991 GO:0007032 IMP involved_in endosome organization 31118240 Process
43991 GO:0007425 IMP involved_in epithelial cell fate determination, open tracheal system 11740943 Process
43991 GO:0007552 IMP involved_in metamorphosis 16182527 Process
43991 GO:0008104 IMP involved_in protein localization 23853710 Process
43991 GO:0008285 IMP involved_in negative regulation of cell population proliferation 10556061,10617573 Process
43991 GO:0008360 IMP involved_in regulation of cell shape 10617573,23707736 Process
43991 GO:0008361 IMP involved_in regulation of cell size 10617573 Process
43991 GO:0009887 IMP involved_in animal organ morphogenesis 10790335 Process
43991 GO:0009888 IMP involved_in tissue development 10790335 Process
43991 GO:0010506 IMP involved_in regulation of autophagy 22952930 Process
43991 GO:0010888 IMP involved_in negative regulation of lipid storage 17079271 Process
43991 GO:0014067 IGI involved_in negative regulation of phosphatidylinositol 3-kinase signaling 10556061 Process
43991 GO:0014067 IMP involved_in negative regulation of phosphatidylinositol 3-kinase signaling 10823906,11832249,12841848,30540251 Process
43991 GO:0030036 IMP involved_in actin cytoskeleton organization 15743877 Process
43991 GO:0030308 IMP involved_in negative regulation of cell growth 21951762 Process
43991 GO:0030707 IMP involved_in follicle cell of egg chamber development 26205122 Process
43991 GO:0031104 IMP involved_in dendrite regeneration 22759636 Process
43991 GO:0035011 IMP involved_in melanotic encapsulation of foreign target 21947570 Process
43991 GO:0035069 IGI involved_in larval midgut histolysis 22555456 Process
43991 GO:0035204 IMP involved_in negative regulation of lamellocyte differentiation 22510984 Process
43991 GO:0035206 IMP involved_in regulation of hemocyte proliferation 20688956 Process
43991 GO:0035212 IMP involved_in cell competition in a multicellular organism 26287461 Process
43991 GO:0040014 IMP involved_in regulation of multicellular organism growth 16182527 Process
43991 GO:0040015 IMP involved_in negative regulation of multicellular organism growth 12163412 Process
43991 GO:0042052 IMP involved_in rhabdomere development 16431366 Process
43991 GO:0042059 IMP involved_in negative regulation of epidermal growth factor receptor signaling pathway 35468055 Process
43991 GO:0042594 IMP involved_in response to starvation 12163412 Process
43991 GO:0042690 IMP involved_in negative regulation of crystal cell differentiation 22510984 Process
43991 GO:0043065 IMP involved_in positive regulation of apoptotic process 10556061 Process
43991 GO:0043491 IGI involved_in protein kinase B signaling 10790335 Process
43991 GO:0045571 IMP involved_in negative regulation of imaginal disc growth 29719260 Process
43991 GO:0045614 IMP involved_in negative regulation of plasmatocyte differentiation 22510984 Process
43991 GO:0045792 IMP involved_in negative regulation of cell size 10556061 Process
43991 GO:0046621 IMP involved_in negative regulation of organ growth 10962553 Process
43991 GO:0046627 IGI involved_in negative regulation of insulin receptor signaling pathway 10556061,12163412 Process
43991 GO:0046627 IMP involved_in negative regulation of insulin receptor signaling pathway 10823906,11832249 Process
43991 GO:0048167 IMP involved_in regulation of synaptic plasticity 30540251 Process
43991 GO:0048542 IMP involved_in lymph gland development 22510984 Process
43991 GO:0048681 IMP involved_in negative regulation of axon regeneration 22759636 Process
43991 GO:0050773 IMP involved_in regulation of dendrite development 19778508 Process
43991 GO:0051726 IMP involved_in regulation of cell cycle 23853709 Process
43991 GO:0051898 IGI involved_in negative regulation of protein kinase B signaling 17369395 Process
43991 GO:0051898 IMP involved_in negative regulation of protein kinase B signaling 10823906,10962553 Process
43991 GO:0055088 IMP involved_in lipid homeostasis 17136098 Process
43991 GO:0071711 IMP involved_in basement membrane organization 24828534 Process
43991 GO:0090175 IMP involved_in regulation of establishment of planar polarity 23707736 Process
43991 GO:1901888 IMP involved_in regulation of cell junction assembly 23707736 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
43991 GO:0004721 IMP enables phosphoprotein phosphatase activity 10556061 Function
43991 GO:0004722 IMP enables protein serine/threonine phosphatase activity 15808505 Function
43991 GO:0016314 IGI enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity 10617573 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
43991 GO:0010008 IMP located_in endosome membrane 31118240 Component