Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 4609
  • Symbol: MYC
  • Description: MYC proto-oncogene, bHLH transcription factor

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4609 GO:0000082 IDA involved_in G1/S transition of mitotic cell cycle 25438055 Process
4609 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 9924025,10412034,18393360,19160485 Process
4609 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 19786833 Process
4609 GO:0000165 IMP involved_in MAPK cascade 17873522 Process
4609 GO:0006338 IDA involved_in chromatin remodeling 21533051 Process
4609 GO:0006879 IDA involved_in intracellular iron ion homeostasis 9924025 Process
4609 GO:0006974 IDA involved_in DNA damage response 17873522 Process
4609 GO:0008284 IDA acts_upstream_of_or_within positive regulation of cell population proliferation 15994933 Process
4609 GO:0009410 IEP involved_in response to xenobiotic stimulus 18291362 Process
4609 GO:0010332 IDA involved_in response to gamma radiation 19179467 Process
4609 GO:0010468 IDA acts_upstream_of_or_within regulation of gene expression 21447833 Process
4609 GO:0010564 IDA involved_in regulation of cell cycle process 8782822 Process
4609 GO:0010628 IDA involved_in positive regulation of gene expression 15459207 Process
4609 GO:0010628 IGI involved_in positive regulation of gene expression 15459207 Process
4609 GO:0032204 IMP involved_in regulation of telomere maintenance 17765874 Process
4609 GO:0032986 IDA involved_in protein-DNA complex disassembly 19160485 Process
4609 GO:0034644 IEP involved_in cellular response to UV 17873522 Process
4609 GO:0043280 IDA involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 19179467 Process
4609 GO:0045656 IMP involved_in negative regulation of monocyte differentiation 9924025 Process
4609 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 8425218,10962037,17558397,18818310 Process
4609 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 10723141 Process
4609 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 9924025 Process
4609 GO:0048146 IDA involved_in positive regulation of fibroblast proliferation 9924025,18987311 Process
4609 GO:0048146 IMP involved_in positive regulation of fibroblast proliferation 15674325 Process
4609 GO:0048147 IDA involved_in negative regulation of fibroblast proliferation 10962037 Process
4609 GO:0050679 IDA involved_in positive regulation of epithelial cell proliferation 18987311 Process
4609 GO:0051276 IDA involved_in chromosome organization 10962037 Process
4609 GO:0051782 IDA involved_in negative regulation of cell division 10962037 Process
4609 GO:0070371 IDA involved_in ERK1 and ERK2 cascade 15459207 Process
4609 GO:0071456 IDA involved_in cellular response to hypoxia 15459207 Process
4609 GO:0071466 IDA involved_in cellular response to xenobiotic stimulus 17873522,19179467 Process
4609 GO:1902255 IDA involved_in positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 10962037 Process
4609 GO:1902895 IDA involved_in positive regulation of miRNA transcription 27791094 Process
4609 GO:1905643 IMP involved_in positive regulation of DNA methylation 19786833 Process

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4609 GO:0000785 IMP part_of chromatin 12837246 Component
4609 GO:0005634 IDA located_in nucleus 8782822,11793365,15358760,15994933,18393360 Component
4609 GO:0005654 IDA located_in nucleoplasm 17558397 Component
4609 GO:0005730 IDA located_in nucleolus 17558397,25775507 Component
4609 GO:0032991 IDA part_of protein-containing complex 17873522,19160485 Component
4609 GO:0071943 IPI part_of Myc-Max complex 12553908 Component
4609 GO:0090571 IPI part_of RNA polymerase II transcription repressor complex 15992821,18393360 Component

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4609 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 10723141 Function
4609 GO:0000978 IMP enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 19786833 Function
4609 GO:0000981 IDA enables DNA-binding transcription factor activity, RNA polymerase II-specific 9924025 Function
4609 GO:0000981 IMP enables DNA-binding transcription factor activity, RNA polymerase II-specific 25956029 Function
4609 GO:0001046 IDA enables core promoter sequence-specific DNA binding 30873824 Function
4609 GO:0001221 IPI enables transcription coregulator binding 15674325 Function
4609 GO:0001227 IMP enables DNA-binding transcription repressor activity, RNA polymerase II-specific 19786833 Function
4609 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 10723141,27791094 Function
4609 GO:0005515 IPI enables protein binding 8755740,9308237,9708738,10597290,11891322,12706874,15103331,15..... Function
4609 GO:0044877 IDA enables protein-containing complex binding 18987311 Function
4609 GO:0070888 IDA enables E-box binding 18818310,27791094 Function
4609 GO:0140297 IPI enables DNA-binding transcription factor binding 15674325,19160485 Function
4609 GO:1905761 IPI enables SCF ubiquitin ligase complex binding 12769844,15103331,15150404 Function