Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 4653
  • Symbol: MYOC
  • Description: myocilin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4653 GO:0001649 IDA involved_in osteoblast differentiation 23629661 Process
4653 GO:0001953 IDA involved_in negative regulation of cell-matrix adhesion 17984096 Process
4653 GO:0014068 IDA involved_in positive regulation of phosphatidylinositol 3-kinase signaling 21656515 Process
4653 GO:0030335 IDA involved_in positive regulation of cell migration 21656515 Process
4653 GO:0031175 IMP involved_in neuron projection development 19959812 Process
4653 GO:0035024 IDA involved_in negative regulation of Rho protein signal transduction 17984096 Process
4653 GO:0038031 IMP involved_in non-canonical Wnt signaling pathway via JNK cascade 19188438 Process
4653 GO:0043408 IDA involved_in regulation of MAPK cascade 23629661 Process
4653 GO:0051496 IDA involved_in positive regulation of stress fiber assembly 19188438 Process
4653 GO:0051497 IDA involved_in negative regulation of stress fiber assembly 17984096 Process
4653 GO:0051894 IDA involved_in positive regulation of focal adhesion assembly 18855004 Process
4653 GO:0051897 IDA involved_in positive regulation of protein kinase B signaling 21656515 Process
4653 GO:0051901 IDA involved_in positive regulation of mitochondrial depolarization 17516541 Process
4653 GO:1900026 IDA involved_in positive regulation of substrate adhesion-dependent cell spreading 18855004 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4653 GO:0001968 IPI enables fibronectin binding 11773026 Function
4653 GO:0005109 IPI enables frizzled binding 19188438 Function
4653 GO:0005515 IPI enables protein binding 11773029,12019210,19188438,20926826,23897819,32296183..... Function
4653 GO:0032027 IPI enables myosin light chain binding 11773029 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4653 GO:0005615 IDA located_in extracellular space 17317787 Component
4653 GO:0005741 IDA located_in mitochondrial outer membrane 17516541 Component
4653 GO:0005743 IDA located_in mitochondrial inner membrane 17516541 Component
4653 GO:0005758 IDA located_in mitochondrial intermembrane space 17516541 Component
4653 GO:0005794 IDA located_in Golgi apparatus 11053284 Component
4653 GO:0031410 IDA located_in cytoplasmic vesicle 11431441 Component
4653 GO:0062023 IDA located_in collagen-containing extracellular matrix 11773026 Component
4653 GO:0070062 HDA located_in extracellular exosome 21362503,23533145 Component