Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4719
• Symbol: NDUFS1
• Description: NADH:ubiquinone oxidoreductase core subunit S1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4719	GO:0005515	IPI	enables	protein binding	15186778,30879903,32807793	Function
4719	GO:0008137	IMP	contributes_to	NADH dehydrogenase (ubiquinone) activity	15824269,16478720,16870178	Function
4719	GO:0008137	IMP	enables	NADH dehydrogenase (ubiquinone) activity	30879903,31557978	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4719	GO:0005739	IDA	located_in	mitochondrion	30879903	Component
4719	GO:0005747	IDA	part_of	mitochondrial respiratory chain complex I	12611891	Component
4719	GO:0005747	IMP	part_of	mitochondrial respiratory chain complex I	16478720	Component
4719	GO:0005747	IPI	part_of	mitochondrial respiratory chain complex I	28844695	Component
4719	GO:0005758	IDA	located_in	mitochondrial intermembrane space	15186778	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4719	GO:0006120	IMP	involved_in	mitochondrial electron transport, NADH to ubiquinone	31557978	Process
4719	GO:0008637	IDA	involved_in	apoptotic mitochondrial changes	15186778	Process
4719	GO:0032981	IMP	involved_in	mitochondrial respiratory chain complex I assembly	30879903,31557978	Process
4719	GO:0045333	IMP	involved_in	cellular respiration	15186778,16478720	Process
4719	GO:0046034	IMP	involved_in	ATP metabolic process	15186778	Process
4719	GO:0051881	IMP	involved_in	regulation of mitochondrial membrane potential	15186778,16478720	Process
4719	GO:0072593	IMP	involved_in	reactive oxygen species metabolic process	15186778,16478720,16870178	Process