Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4853
• Symbol: NOTCH2
• Description: notch receptor 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4853	GO:0003184	IMP	involved_in	pulmonary valve morphogenesis	16773578	Process
4853	GO:0007219	IDA	involved_in	Notch signaling pathway	11306509,25985737	Process
4853	GO:0009887	IEP	involved_in	animal organ morphogenesis	12531696	Process
4853	GO:0010629	IDA	involved_in	negative regulation of gene expression	11306509	Process
4853	GO:0010838	IDA	involved_in	positive regulation of keratinocyte proliferation	18469519	Process
4853	GO:0035556	IDA	involved_in	intracellular signal transduction	18469519	Process
4853	GO:0046579	IDA	involved_in	positive regulation of Ras protein signal transduction	11306509	Process
4853	GO:0046849	IMP	involved_in	bone remodeling	21378985,21378989	Process
4853	GO:0060413	IMP	involved_in	atrial septum morphogenesis	16773578	Process
4853	GO:0070374	IDA	involved_in	positive regulation of ERK1 and ERK2 cascade	11306509	Process
4853	GO:0071228	IDA	involved_in	cellular response to tumor cell	11306509	Process
4853	GO:2001204	IMP	involved_in	regulation of osteoclast development	29149593	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4853	GO:0005515	IPI	enables	protein binding	10079256,11101851,11823422,18469519,25985737,29149593,29329397.....	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
4853	GO:0005634	IDA	located_in	nucleus	1303260	Component
4853	GO:0005654	IDA	located_in	nucleoplasm		Component
4853	GO:0005886	IDA	located_in	plasma membrane	9244302,29329397	Component
4853	GO:0009986	IDA	located_in	cell surface	9244302	Component
4853	GO:0016020	HDA	located_in	membrane	19946888	Component
4853	GO:0043235	IDA	part_of	receptor complex	23382219	Component