Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 487
• Symbol: ATP2A1
• Description: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
487	GO:0005388	IDA	enables	P-type calcium transporter activity	8729696	Function
487	GO:0005509	IMP	enables	calcium ion binding	9405806	Function
487	GO:0005515	IPI	enables	protein binding	9295312,28890335	Function
487	GO:0042803	IPI	enables	protein homodimerization activity	11402072	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
487	GO:0006816	IMP	involved_in	calcium ion transport	9405806	Process
487	GO:0008637	IMP	involved_in	apoptotic mitochondrial changes	19061639	Process
487	GO:0031448	IDA	involved_in	positive regulation of fast-twitch skeletal muscle fiber contraction	12479237	Process
487	GO:0032470	IMP	involved_in	positive regulation of endoplasmic reticulum calcium ion concentration	11402072	Process
487	GO:0032471	IMP	involved_in	negative regulation of endoplasmic reticulum calcium ion concentration	11402072,19061639	Process
487	GO:0034976	IMP	involved_in	response to endoplasmic reticulum stress	19061639	Process
487	GO:0051561	IMP	involved_in	positive regulation of mitochondrial calcium ion concentration	19061639	Process
487	GO:0051659	IMP	involved_in	maintenance of mitochondrion location	19061639	Process
487	GO:0070059	IMP	involved_in	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	19061639	Process
487	GO:0070509	IMP	involved_in	calcium ion import	8040329	Process
487	GO:0090076	IDA	involved_in	relaxation of skeletal muscle	8841193	Process