Gene Ontology

Gene Info

• Species: Fly (Drosophila melanogaster)
• GeneID: 49045
• Symbol: Gprk2
• Description: G protein-coupled receptor kinase 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
49045	GO:0003384	IMP	involved_in	apical constriction involved in gastrulation	24026125	Process
49045	GO:0006468	IMP	involved_in	protein phosphorylation	25284370	Process
49045	GO:0006963	IMP	involved_in	positive regulation of antibacterial peptide biosynthetic process	20421637	Process
49045	GO:0007476	IMP	involved_in	imaginal disc-derived wing morphogenesis	17483466,20844016	Process
49045	GO:0010739	IGI	involved_in	positive regulation of protein kinase A signaling	22096079	Process
49045	GO:0045752	IGI	involved_in	positive regulation of Toll signaling pathway	20421637	Process
49045	GO:0045752	IMP	involved_in	positive regulation of Toll signaling pathway	20421637	Process
49045	GO:0045879	IGI	involved_in	negative regulation of smoothened signaling pathway	22096079	Process
49045	GO:0045880	IDA	involved_in	positive regulation of smoothened signaling pathway	25009998	Process
49045	GO:0045880	IGI	involved_in	positive regulation of smoothened signaling pathway	20844016,27280464	Process
49045	GO:0045880	IMP	involved_in	positive regulation of smoothened signaling pathway	17483466,19850026,22306085,26863604,30541874	Process
49045	GO:0048260	IMP	involved_in	positive regulation of receptor-mediated endocytosis	19850026	Process
49045	GO:0048601	IMP	involved_in	oocyte morphogenesis	9217001	Process
49045	GO:0050830	IMP	involved_in	defense response to Gram-positive bacterium	20421637	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
49045	GO:0004674	IDA	enables	protein serine/threonine kinase activity	20844016,25009998,26863604,30541874	Function
49045	GO:0004674	IMP	enables	protein serine/threonine kinase activity	27280464,29438012	Function
49045	GO:0004703	IMP	enables	G protein-coupled receptor kinase activity	9217001	Function
49045	GO:0070273	IDA	enables	phosphatidylinositol-4-phosphate binding	26863604	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
49045	GO:0005737	IDA	located_in	cytoplasm	9217001	Component
49045	GO:0005886	HDA	located_in	plasma membrane	25294944	Component
49045	GO:0005886	IDA	located_in	plasma membrane	9217001	Component
49045	GO:0009898	IDA	located_in	cytoplasmic side of plasma membrane	26863604	Component