Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 4976
  • Symbol: OPA1
  • Description: OPA1 mitochondrial dynamin like GTPase

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4976 GO:0000002 IMP involved_in mitochondrial genome maintenance 18158317 Process
4976 GO:0007005 IMP acts_upstream_of_or_within mitochondrion organization 21149567 Process
4976 GO:0007007 IDA involved_in inner mitochondrial membrane organization 12509422 Process
4976 GO:0007601 IMP involved_in visual perception 11017080 Process
4976 GO:0008053 IDA involved_in mitochondrial fusion 17545159 Process
4976 GO:0008053 IMP involved_in mitochondrial fusion 20185555,20436456 Process
4976 GO:0043066 IDA involved_in negative regulation of apoptotic process 12509422 Process
4976 GO:0046039 IDA involved_in GTP metabolic process 20185555 Process
4976 GO:0051259 IDA involved_in protein complex oligomerization 20185555 Process
4976 GO:0090201 IMP involved_in negative regulation of release of cytochrome c from mitochondria 21149567 Process
4976 GO:0090398 IDA involved_in cellular senescence 17545159 Process
4976 GO:0097749 IDA involved_in membrane tubulation 20185555 Process
4976 GO:1902236 IGI involved_in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 23453807 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4976 GO:0003924 IDA enables GTPase activity 20185555,27667664 Function
4976 GO:0005515 IPI enables protein binding 20436456,21081504,21364629,24282027,24344202,28746876,31046837..... Function
4976 GO:0070300 IDA enables phosphatidic acid binding 20185555 Function
4976 GO:1901612 IDA enables cardiolipin binding 20185555 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
4976 GO:0005654 IDA located_in nucleoplasm Component
4976 GO:0005739 IDA located_in mitochondrion 17545159 Component
4976 GO:0005741 IDA located_in mitochondrial outer membrane 12504110 Component
4976 GO:0005758 IDA located_in mitochondrial intermembrane space 17008324 Component
4976 GO:0005829 IDA located_in cytosol Component
4976 GO:0016020 HDA located_in membrane 19946888 Component
4976 GO:0030061 IDA located_in mitochondrial crista 12504110 Component