Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 5428
  • Symbol: POLG
  • Description: DNA polymerase gamma, catalytic subunit

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5428 GO:0002020 IPI enables protease binding 14739292 Function
5428 GO:0003677 IDA enables DNA binding 10608893 Function
5428 GO:0003682 IDA enables chromatin binding 18063578 Function
5428 GO:0003887 IDA enables DNA-directed DNA polymerase activity 10608893,15164064,15177179,19837034,19858216,26123486,26446790..... Function
5428 GO:0003887 IMP enables DNA-directed DNA polymerase activity 26554610 Function
5428 GO:0005515 IPI enables protein binding 10608893,16263719,16488880,17762861,19837034,26496610,28514442..... Function
5428 GO:0008408 IDA enables 3'-5' exonuclease activity 28430993 Function
5428 GO:0008408 IMP enables 3'-5' exonuclease activity 26554610 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5428 GO:0005739 IDA located_in mitochondrion Component
5428 GO:0005759 IDA located_in mitochondrial matrix 19837034 Component
5428 GO:0005760 IDA part_of gamma DNA polymerase complex 10608893,19837034,19858216,26123486,26446790,26554610..... Component
5428 GO:0005760 IPI part_of gamma DNA polymerase complex 19837034 Component
5428 GO:0032991 IDA part_of protein-containing complex 25378300 Component
5428 GO:0042645 IDA located_in mitochondrial nucleoid 18063578 Component
5428 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5428 GO:0006261 IDA involved_in DNA-templated DNA replication 10608893,15167897,19837034,19858216,26123486,26446790,28430993..... Process
5428 GO:0006264 IDA involved_in mitochondrial DNA replication 19837034 Process
5428 GO:0006264 IMP involved_in mitochondrial DNA replication 26554610 Process
5428 GO:0006287 IDA acts_upstream_of_or_within base-excision repair, gap-filling 15177179 Process