Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 5444
  • Symbol: PON1
  • Description: paraoxonase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5444 GO:0004063 IDA enables aryldialkylphosphatase activity 7638166,15098021 Function
5444 GO:0004064 IDA enables arylesterase activity 7638166,15098021 Function
5444 GO:0005509 IDA enables calcium ion binding 15098021 Function
5444 GO:0005543 IDA enables phospholipid binding 10479665 Function
5444 GO:0042803 IDA enables protein homodimerization activity 15772423 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5444 GO:0005615 IDA located_in extracellular space 7638166 Component
5444 GO:0034364 IDA part_of high-density lipoprotein particle 15721011 Component
5444 GO:0034366 IDA part_of spherical high-density lipoprotein particle 16682745 Component
5444 GO:0070062 HDA located_in extracellular exosome 23533145 Component
5444 GO:0072562 HDA located_in blood microparticle 22516433 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5444 GO:0010875 IDA involved_in positive regulation of cholesterol efflux 15721011 Process
5444 GO:0019439 IDA involved_in aromatic compound catabolic process 15772423 Process
5444 GO:0032411 IDA involved_in positive regulation of transporter activity 15721011 Process
5444 GO:0034445 IDA NOT involved_in negative regulation of plasma lipoprotein oxidation 15342686 Process
5444 GO:0046395 IDA involved_in carboxylic acid catabolic process 7638166 Process
5444 GO:0046434 IDA involved_in organophosphate catabolic process 7638166 Process
5444 GO:0046470 IDA involved_in phosphatidylcholine metabolic process 15721011 Process
5444 GO:0051099 IDA involved_in positive regulation of binding 15721011 Process