Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 5530
  • Symbol: PPP3CA
  • Description: protein phosphatase 3 catalytic subunit alpha

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5530 GO:0004722 IDA enables protein serine/threonine phosphatase activity 30718414 Function
5530 GO:0004722 IMP enables protein serine/threonine phosphatase activity 30611118 Function
5530 GO:0005515 IPI enables protein binding 8524402,11114196,11842093,12218175,12357034,12577067,12809556,..... Function
5530 GO:0005516 IDA enables calmodulin binding 11005320,18384083,19404396 Function
5530 GO:0016018 IDA enables cyclosporin A binding 12218175,12357034 Function
5530 GO:0019899 IDA enables enzyme binding 11005320 Function
5530 GO:0033192 IDA enables calmodulin-dependent protein phosphatase activity 18815128,19154138,23468591 Function
5530 GO:0033192 IMP enables calmodulin-dependent protein phosphatase activity 30254215 Function
5530 GO:0046983 IPI enables protein dimerization activity 11005320 Function
5530 GO:0051117 IPI enables ATPase binding 15955804 Function
5530 GO:0140677 EXP enables molecular function activator activity 24018048,24191726,27187005 Function
5530 GO:0140677 IDA enables molecular function activator activity 24018048 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5530 GO:0005654 IDA located_in nucleoplasm Component
5530 GO:0005737 IDA located_in cytoplasm 15955804,19154138,22343722 Component
5530 GO:0005829 IDA located_in cytosol Component
5530 GO:0005886 IDA located_in plasma membrane 15955804,28881575 Component
5530 GO:0005955 IDA part_of calcineurin complex 12218175,12357034,22343722,22688515,23468591,27974827..... Component
5530 GO:0009898 IDA colocalizes_with cytoplasmic side of plasma membrane 22343722 Component
5530 GO:0043197 IDA located_in dendritic spine 22343722 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5530 GO:0006470 IDA involved_in protein dephosphorylation 18815128,19154138 Process
5530 GO:0030335 IMP involved_in positive regulation of cell migration 20422345,21785830 Process
5530 GO:0033173 IDA involved_in calcineurin-NFAT signaling cascade 19154138,22688515 Process
5530 GO:0033173 IMP involved_in calcineurin-NFAT signaling cascade 15955804,22343722,23468591,26248042 Process
5530 GO:0045785 IMP involved_in positive regulation of cell adhesion 21785830 Process
5530 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 22688515 Process
5530 GO:0051592 IDA involved_in response to calcium ion 18815128 Process
5530 GO:0070262 IMP involved_in peptidyl-serine dephosphorylation 30611118 Process
5530 GO:0097720 IMP involved_in calcineurin-mediated signaling 11005320 Process