Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5594
• Symbol: MAPK1
• Description: mitogen-activated protein kinase 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5594	GO:0004674	IDA	enables	protein serine/threonine kinase activity	7588608,15850461,18794356,22031296,26996940	Function
5594	GO:0005515	IPI	enables	protein binding	9632734,10415025,10601328,11489891,12592337,12840032,15133037,.....	Function
5594	GO:0019902	IPI	enables	phosphatase binding	19494114	Function
5594	GO:0042802	IPI	enables	identical protein binding	16627622,26267534	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5594	GO:0005634	HDA	located_in	nucleus	16791210	Component
5594	GO:0005634	IDA	located_in	nucleus	18794356,32721402	Component
5594	GO:0005737	HDA	located_in	cytoplasm	16791210	Component
5594	GO:0005737	IDA	located_in	cytoplasm	18794356,32721402	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5594	GO:0006468	IDA	involved_in	protein phosphorylation	23184662	Process
5594	GO:0010759	IGI	acts_upstream_of	positive regulation of macrophage chemotaxis	26754294	Process
5594	GO:0010800	IDA	involved_in	positive regulation of peptidyl-threonine phosphorylation	16314496	Process
5594	GO:0018105	IDA	involved_in	peptidyl-serine phosphorylation	15850461	Process
5594	GO:0030521	IMP	involved_in	androgen receptor signaling pathway	22031296	Process
5594	GO:0032212	IMP	involved_in	positive regulation of telomere maintenance via telomerase	21531765	Process
5594	GO:0034198	IDA	involved_in	cellular response to amino acid starvation	11096076	Process
5594	GO:0034614	IMP	involved_in	cellular response to reactive oxygen species	26514923	Process
5594	GO:0038127	IDA	involved_in	ERBB signaling pathway	15133037	Process
5594	GO:0043401	IMP	involved_in	steroid hormone mediated signaling pathway	22031296	Process
5594	GO:0050847	IMP	involved_in	progesterone receptor signaling pathway	22031296	Process
5594	GO:0051403	IDA	involved_in	stress-activated MAPK cascade	11096076	Process
5594	GO:0051973	IMP	involved_in	positive regulation of telomerase activity	21531765	Process
5594	GO:0070371	IDA	involved_in	ERK1 and ERK2 cascade	16314496,22031296	Process
5594	GO:0070849	IDA	involved_in	response to epidermal growth factor	18794356	Process
5594	GO:0071276	IMP	involved_in	cellular response to cadmium ion	26514923	Process
5594	GO:0120041	IGI	acts_upstream_of	positive regulation of macrophage proliferation	26754294	Process
5594	GO:1904355	IMP	involved_in	positive regulation of telomere capping	21531765	Process