Gene Ontology

Gene Info

• Species: Mouse (Mus musculus)
• GeneID: 56484
• Symbol: Foxo3
• Description: forkhead box O3

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56484	GO:0000122	IDA	involved_in	negative regulation of transcription by RNA polymerase II	21621563	Process
56484	GO:0001542	IMP	acts_upstream_of_or_within	ovulation from ovarian follicle	12855809	Process
56484	GO:0001544	IMP	acts_upstream_of_or_within	initiation of primordial ovarian follicle growth	12855809	Process
56484	GO:0001547	IMP	acts_upstream_of_or_within	antral ovarian follicle growth	14978268	Process
56484	GO:0001556	IMP	acts_upstream_of_or_within	oocyte maturation	12855809	Process
56484	GO:0006355	IDA	acts_upstream_of_or_within	regulation of DNA-templated transcription	12930811	Process
56484	GO:0006357	IDA	involved_in	regulation of transcription by RNA polymerase II	17521387	Process
56484	GO:0006390	IMP	involved_in	mitochondrial transcription	23283301	Process
56484	GO:0010508	IDA	involved_in	positive regulation of autophagy	18054315,18054316	Process
56484	GO:0014737	IDA	involved_in	positive regulation of muscle atrophy	18054315,18054316	Process
56484	GO:0030330	IDA	acts_upstream_of_or_within	DNA damage response, signal transduction by p53 class mediator	15383658	Process
56484	GO:0034599	IDA	involved_in	cellular response to oxidative stress	17521387	Process
56484	GO:0034599	IGI	acts_upstream_of_or_within	cellular response to oxidative stress	24483844	Process
56484	GO:0042593	IMP	acts_upstream_of_or_within	glucose homeostasis	12855809	Process
56484	GO:0042594	IDA	involved_in	response to starvation	18054315,18054316	Process
56484	GO:0045893	IDA	acts_upstream_of_or_within	positive regulation of DNA-templated transcription	12048180	Process
56484	GO:0045893	IDA	involved_in	positive regulation of DNA-templated transcription	18054315,18054316	Process
56484	GO:0048854	IGI	acts_upstream_of_or_within	brain morphogenesis	24483844	Process
56484	GO:0060070	IGI	acts_upstream_of	canonical Wnt signaling pathway	19896444	Process
56484	GO:0070542	IDA	involved_in	response to fatty acid	32103177	Process
56484	GO:0090090	IGI	acts_upstream_of_or_within	negative regulation of canonical Wnt signaling pathway	19896444	Process
56484	GO:0097150	IGI	acts_upstream_of_or_within	neuronal stem cell population maintenance	19896444,24483844	Process
56484	GO:0097192	IGI	acts_upstream_of_or_within	extrinsic apoptotic signaling pathway in absence of ligand	12431371	Process
56484	GO:1902895	IMP	involved_in	positive regulation of miRNA transcription	19933931	Process
56484	GO:2000177	IGI	acts_upstream_of_or_within	regulation of neural precursor cell proliferation	19896444	Process
56484	GO:2000377	IGI	acts_upstream_of_or_within	regulation of reactive oxygen species metabolic process	19896444	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56484	GO:0000976	IDA	enables	transcription cis-regulatory region binding	19933931	Function
56484	GO:0000978	IDA	enables	RNA polymerase II cis-regulatory region sequence-specific DNA binding	17521387	Function
56484	GO:0001227	IGI	enables	DNA-binding transcription repressor activity, RNA polymerase II-specific	19896444	Function
56484	GO:0001228	IDA	enables	DNA-binding transcription activator activity, RNA polymerase II-specific	19933931,32103177	Function
56484	GO:0003677	IDA	enables	DNA binding	14966295,15383658	Function
56484	GO:0003700	IDA	enables	DNA-binding transcription factor activity	14966295,15322035,18054315,18054316	Function
56484	GO:0005515	IPI	enables	protein binding	17521387,22402663,22510882,23283301	Function
56484	GO:0031490	IDA	enables	chromatin DNA binding	17521387	Function
56484	GO:0034246	IMP	enables	mitochondrial transcription factor activity	23283301	Function
56484	GO:0043565	IDA	enables	sequence-specific DNA binding	11353388	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56484	GO:0005634	IDA	located_in	nucleus	12857750,14966295,18054315,23283301,32103177	Component
56484	GO:0005737	IDA	located_in	cytoplasm	12857750,14966295,15383658,23283301,32103177	Component
56484	GO:0005739	IDA	colocalizes_with	mitochondrion	23283301	Component
56484	GO:0005741	IDA	located_in	mitochondrial outer membrane	29445193	Component
56484	GO:0005759	IDA	colocalizes_with	mitochondrial matrix	29445193	Component
56484	GO:0005829	IDA	located_in	cytosol	18054315	Component
56484	GO:0016020	IDA	located_in	membrane	15383658	Component
56484	GO:0032991	IDA	part_of	protein-containing complex	23283301	Component