Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 56652
• Symbol: TWNK
• Description: twinkle mtDNA helicase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56652	GO:0002020	IPI	enables	protease binding	14739292	Function
56652	GO:0003697	IDA	enables	single-stranded DNA binding	18971204	Function
56652	GO:0042802	IPI	enables	identical protein binding	18971204	Function
56652	GO:0043139	IDA	enables	5'-3' DNA helicase activity	12975372,15167897,18971204	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56652	GO:0006264	IMP	involved_in	mitochondrial DNA replication	18971204	Process
56652	GO:0006268	IDA	involved_in	DNA unwinding involved in DNA replication	15167897	Process
56652	GO:0006390	IMP	involved_in	mitochondrial transcription	18971204	Process
56652	GO:0034214	IDA	involved_in	protein hexamerization	18971204	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56652	GO:0042645	IDA	located_in	mitochondrial nucleoid	18063578,18971204	Component