Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 57104
• Symbol: PNPLA2
• Description: patatin like domain 2, triacylglycerol lipase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57104	GO:0004623	IDA	enables	phospholipase A2 activity	15364929,17032652	Function
57104	GO:0004806	EXP	enables	triglyceride lipase activity	17603008	Function
57104	GO:0004806	IDA	enables	triglyceride lipase activity	15364929,15550674,16150821,17603008,34903883	Function
57104	GO:0004806	IMP	enables	triglyceride lipase activity	16239926	Function
57104	GO:0005515	IPI	enables	protein binding	17032652	Function
57104	GO:0016411	IDA	enables	acylglycerol O-acyltransferase activity	17603008	Function
57104	GO:0050253	EXP	enables	retinyl-palmitate esterase activity	17603008	Function
57104	GO:0051264	IDA	enables	mono-olein transacylation activity	15364929	Function
57104	GO:0051265	IDA	enables	diolein transacylation activity	15364929	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57104	GO:0005654	IDA	located_in	nucleoplasm		Component
57104	GO:0005811	IDA	is_active_in	lipid droplet	34903883	Component
57104	GO:0005811	IDA	located_in	lipid droplet	16239926,21498505	Component
57104	GO:0005886	IDA	located_in	plasma membrane	17032652	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57104	GO:0010891	IDA	involved_in	negative regulation of sequestering of triglyceride	16679289	Process
57104	GO:0010898	IDA	involved_in	positive regulation of triglyceride catabolic process	16679289	Process
57104	GO:1905691	IMP	involved_in	lipid droplet disassembly	16239926	Process