Gene Ontology

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 57192
• Symbol: MCOLN1
• Description: mucolipin TRP cation channel 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57192	GO:0005515	IPI	enables	protein binding	21224396,25130899,32296183	Function
57192	GO:0042802	IPI	enables	identical protein binding	29019983,30305615	Function
57192	GO:0099604	IDA	enables	ligand-gated calcium channel activity	25720963,29019983	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57192	GO:0005654	IDA	located_in	nucleoplasm		Component
57192	GO:0005764	IDA	located_in	lysosome	21224396	Component
57192	GO:0005765	HDA	located_in	lysosomal membrane	17897319	Component
57192	GO:0005765	IDA	is_active_in	lysosomal membrane	25720963	Component
57192	GO:0005770	IDA	located_in	late endosome	21224396	Component
57192	GO:0005794	IDA	located_in	Golgi apparatus		Component
57192	GO:0016020	IDA	located_in	membrane	29019983	Component
57192	GO:0043231	IDA	located_in	intracellular membrane-bounded organelle		Component
57192	GO:0043235	IDA	part_of	receptor complex	23382219	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57192	GO:0051289	IDA	involved_in	protein homotetramerization	29019983	Process
57192	GO:0070588	IDA	involved_in	calcium ion transmembrane transport	29019983	Process
57192	GO:0090382	IDA	involved_in	phagosome maturation	27623384	Process
57192	GO:1901660	IDA	involved_in	calcium ion export	25720963	Process
57192	GO:1905673	IDA	involved_in	positive regulation of lysosome organization	25720963	Process