Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 57320
  • Symbol: Park7
  • Description: Parkinson disease (autosomal recessive, early onset) 7

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57320 GO:0001963 IMP acts_upstream_of_or_within synaptic transmission, dopaminergic 15799973 Process
57320 GO:0002866 IMP involved_in positive regulation of acute inflammatory response to antigenic stimulus 26021615 Process
57320 GO:0006979 IMP involved_in response to oxidative stress 15784737 Process
57320 GO:0007005 IMP involved_in mitochondrion organization 20186336 Process
57320 GO:0008344 IMP acts_upstream_of_or_within adult locomotory behavior 15721235,15799973 Process
57320 GO:0010273 IMP involved_in detoxification of copper ion 23792957 Process
57320 GO:0010628 IMP involved_in positive regulation of gene expression 22492997 Process
57320 GO:0030073 IMP involved_in insulin secretion 22611253 Process
57320 GO:0031397 IMP involved_in negative regulation of protein ubiquitination 24899725 Process
57320 GO:0033864 IMP involved_in positive regulation of NAD(P)H oxidase activity 26021615 Process
57320 GO:0034599 IMP involved_in cellular response to oxidative stress 21068725 Process
57320 GO:0034614 IMP acts_upstream_of_or_within cellular response to reactive oxygen species 16624565 Process
57320 GO:0036471 IMP involved_in cellular response to glyoxal 22523093 Process
57320 GO:0042177 IMP involved_in negative regulation of protein catabolic process 24899725 Process
57320 GO:0042542 IDA acts_upstream_of_or_within response to hydrogen peroxide 15784737 Process
57320 GO:0042542 IMP acts_upstream_of_or_within response to hydrogen peroxide 15784737 Process
57320 GO:0042593 IMP involved_in glucose homeostasis 22611253 Process
57320 GO:0042743 IMP acts_upstream_of_or_within hydrogen peroxide metabolic process 17766438 Process
57320 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 17015834,21097510 Process
57320 GO:0046295 IDA involved_in glycolate biosynthetic process 22523093 Process
57320 GO:0050727 IMP involved_in regulation of inflammatory response 19276172 Process
57320 GO:0050787 IMP involved_in detoxification of mercury ion 23792957 Process
57320 GO:0050821 IMP involved_in protein stabilization 17015834,19229105 Process
57320 GO:0051583 IMP acts_upstream_of_or_within dopamine uptake involved in synaptic transmission 15721235 Process
57320 GO:0051899 IMP acts_upstream_of_or_within membrane depolarization 16624565 Process
57320 GO:0060081 IMP acts_upstream_of_or_within membrane hyperpolarization 16624565 Process
57320 GO:0070994 IMP involved_in detection of oxidative stress 17766438 Process
57320 GO:1902176 IMP acts_upstream_of negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 22523093 Process
57320 GO:1902177 IMP acts_upstream_of_or_within positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 22555455 Process
57320 GO:1902236 IMP involved_in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 14652021 Process
57320 GO:1902958 IMP involved_in positive regulation of mitochondrial electron transport, NADH to ubiquinone 19822128 Process
57320 GO:1903189 IDA involved_in glyoxal metabolic process 22523093 Process
57320 GO:1903377 IMP involved_in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 24899725 Process
57320 GO:1903384 IMP involved_in negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway 14652021 Process
57320 GO:1903427 IMP involved_in negative regulation of reactive oxygen species biosynthetic process 22611253 Process
57320 GO:1903428 IDA acts_upstream_of_or_within positive regulation of reactive oxygen species biosynthetic process 22555455 Process
57320 GO:1903751 IMP involved_in negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide 24947010 Process
57320 GO:2000277 IMP involved_in positive regulation of oxidative phosphorylation uncoupler activity 21068725 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57320 GO:0005515 IPI enables protein binding 14752510,24947010,26021615,31536960 Function
57320 GO:0019826 IMP enables oxygen sensor activity 17766438 Function
57320 GO:0051920 IMP enables peroxiredoxin activity 17766438 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57320 GO:0005634 IDA located_in nucleus 22555455 Component
57320 GO:0005739 HDA located_in mitochondrion 18614015 Component
57320 GO:0005739 IDA located_in mitochondrion 15944198,17766438,20969476,22555455,31536960 Component
57320 GO:0005758 IDA located_in mitochondrial intermembrane space 15944198 Component
57320 GO:0005759 IDA located_in mitochondrial matrix 15944198 Component
57320 GO:0005783 IDA located_in endoplasmic reticulum 22555455,31536960 Component
57320 GO:0005829 IDA located_in cytosol 15944198,20969476,22555455 Component
57320 GO:0043005 IDA located_in neuron projection 24947010 Component
57320 GO:0044297 IDA located_in cell body 24947010 Component