Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 57617
  • Symbol: VPS18
  • Description: VPS18 core subunit of CORVET and HOPS complexes

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57617 GO:0005515 IPI enables protein binding 11382755,20434987,23434281,23901104,23918659,24554770,25783203..... Function
57617 GO:0019905 IDA enables syntaxin binding 11382755 Function
57617 GO:0061630 IMP enables ubiquitin protein ligase activity 31015428 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57617 GO:0005764 IDA located_in lysosome 11382755,21802320 Component
57617 GO:0005765 HDA located_in lysosomal membrane 17897319 Component
57617 GO:0005770 IDA located_in late endosome 11382755 Component
57617 GO:0030897 IDA part_of HOPS complex 19109425,23901104 Component
57617 GO:0098978 EXP is_active_in glutamatergic synapse 17027648 Component
57617 GO:0098978 IDA is_active_in glutamatergic synapse 17027648 Component
57617 GO:0098978 IMP is_active_in glutamatergic synapse 17027648 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57617 GO:0007032 IDA involved_in endosome organization 18799622 Process
57617 GO:0007040 IDA involved_in lysosome organization 18799622 Process
57617 GO:0008333 IMP involved_in endosome to lysosome transport 25783203 Process
57617 GO:0016567 IMP involved_in protein ubiquitination 31015428 Process
57617 GO:0033147 IGI involved_in negative regulation of intracellular estrogen receptor signaling pathway 31015428 Process
57617 GO:2000300 EXP involved_in regulation of synaptic vesicle exocytosis 17027648 Process
57617 GO:2000300 IDA involved_in regulation of synaptic vesicle exocytosis 17027648 Process
57617 GO:2000300 IMP involved_in regulation of synaptic vesicle exocytosis 17027648 Process