Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 57680
  • Symbol: CHD8
  • Description: chromodomain helicase DNA binding protein 8

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57680 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 25294932 Process
57680 GO:0006338 IMP involved_in chromatin remodeling 18378692 Process
57680 GO:0007420 IMP involved_in brain development 24998929 Process
57680 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 18378692 Process
57680 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 17938208 Process
57680 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 17938208,25294932 Process
57680 GO:0045945 IMP involved_in positive regulation of transcription by RNA polymerase III 17938208 Process
57680 GO:0048565 IMP involved_in digestive tract development 24998929 Process
57680 GO:0090090 IDA acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway 22083958 Process
57680 GO:0090090 IDA involved_in negative regulation of canonical Wnt signaling pathway 18378692 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57680 GO:0003677 IMP enables DNA binding 18378692 Function
57680 GO:0003682 IDA enables chromatin binding 22083958 Function
57680 GO:0005515 IPI enables protein binding 15960975,17938208,18378692,20085832,20453063,26816381,26949739..... Function
57680 GO:0005524 IDA enables ATP binding 18378692 Function
57680 GO:0008013 IDA enables beta-catenin binding 18378692,22083958 Function
57680 GO:0035064 IDA enables methylated histone binding 17938208 Function
57680 GO:0140658 IDA enables ATP-dependent chromatin remodeler activity 18378692 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
57680 GO:0005634 IDA located_in nucleus 18378692,20453063 Component
57680 GO:0005654 IDA located_in nucleoplasm Component
57680 GO:0032991 IDA part_of protein-containing complex 18378692 Component
57680 GO:0071339 IDA part_of MLL1 complex 15960975 Component