Gene Ontology

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 58234
  • Symbol: Shank3
  • Description: SH3 and multiple ankyrin repeat domains 3

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
58234 GO:0000165 IGI acts_upstream_of_or_within MAPK cascade 15569713 Process
58234 GO:0001838 IGI acts_upstream_of_or_within embryonic epithelial tube formation 15569713 Process
58234 GO:0007416 IMP involved_in synapse assembly 21423165 Process
58234 GO:0007611 IMP acts_upstream_of_or_within learning or memory 21558424 Process
58234 GO:0007612 IMP involved_in learning 21558424 Process
58234 GO:0007613 IMP involved_in memory 21558424 Process
58234 GO:0007626 IMP acts_upstream_of_or_within locomotory behavior 21558424 Process
58234 GO:0008306 IMP involved_in associative learning 26158416 Process
58234 GO:0010467 IMP involved_in gene expression 30116174 Process
58234 GO:0014009 IMP involved_in glial cell proliferation 27785461 Process
58234 GO:0021773 IMP involved_in striatal medium spiny neuron differentiation 21423165 Process
58234 GO:0032232 IDA acts_upstream_of_or_within negative regulation of actin filament bundle assembly 19208628 Process
58234 GO:0035176 IMP acts_upstream_of_or_within social behavior 21558424 Process
58234 GO:0035176 IMP involved_in social behavior 21167025,21423165,31853066 Process
58234 GO:0035640 IMP involved_in exploration behavior 21558424 Process
58234 GO:0035641 IMP involved_in locomotory exploration behavior 21423165,21558424 Process
58234 GO:0040011 IMP involved_in locomotion 21558424 Process
58234 GO:0045794 IMP involved_in negative regulation of cell volume 21423165 Process
58234 GO:0048167 IMP acts_upstream_of_or_within regulation of synaptic plasticity 21558424 Process
58234 GO:0048170 IMP involved_in positive regulation of long-term neuronal synaptic plasticity 21167025 Process
58234 GO:0048854 IMP involved_in brain morphogenesis 21423165 Process
58234 GO:0050804 IDA involved_in modulation of chemical synaptic transmission 27161151 Process
58234 GO:0050804 IEP involved_in modulation of chemical synaptic transmission 27161151 Process
58234 GO:0050804 IMP involved_in modulation of chemical synaptic transmission 27161151 Process
58234 GO:0050885 IMP involved_in neuromuscular process controlling balance 21558424 Process
58234 GO:0051835 IMP involved_in positive regulation of synapse structural plasticity 21167025 Process
58234 GO:0051968 IMP involved_in positive regulation of synaptic transmission, glutamatergic 21167025,21423165,21795692 Process
58234 GO:0060291 IMP involved_in long-term synaptic potentiation 21558424 Process
58234 GO:0060292 IMP involved_in long-term synaptic depression 21795692 Process
58234 GO:0060997 IMP acts_upstream_of_or_within dendritic spine morphogenesis 21558424 Process
58234 GO:0060997 IMP involved_in dendritic spine morphogenesis 21167025,21423165 Process
58234 GO:0060999 IMP involved_in positive regulation of dendritic spine development 21795692 Process
58234 GO:0061001 IMP involved_in regulation of dendritic spine morphogenesis 21795692 Process
58234 GO:0061351 IMP involved_in neural precursor cell proliferation 27785461 Process
58234 GO:0071625 IMP acts_upstream_of_or_within vocalization behavior 21558424 Process
58234 GO:0071625 IMP involved_in vocalization behavior 21167025 Process
58234 GO:0097107 IMP involved_in postsynaptic density assembly 21423165 Process
58234 GO:0097113 IMP involved_in AMPA glutamate receptor clustering 21558424,21795692 Process
58234 GO:0097114 IMP involved_in NMDA glutamate receptor clustering 21558424 Process
58234 GO:0097117 IMP involved_in guanylate kinase-associated protein clustering 21558424 Process
58234 GO:0097396 IMP involved_in response to interleukin-17 31853066 Process
58234 GO:1900271 IMP involved_in regulation of long-term synaptic potentiation 21558424 Process
58234 GO:1900273 IMP involved_in positive regulation of long-term synaptic potentiation 21167025 Process
58234 GO:1900451 IMP involved_in positive regulation of glutamate receptor signaling pathway 21795692 Process
58234 GO:1900452 IMP involved_in regulation of long-term synaptic depression 21795692 Process
58234 GO:1904717 IMP acts_upstream_of_or_within regulation of AMPA glutamate receptor clustering 21558424 Process
58234 GO:2000463 IMP involved_in positive regulation of excitatory postsynaptic potential 21167025,21423165,21795692 Process
58234 GO:2000821 IMP involved_in regulation of grooming behavior 21423165,21558424 Process
58234 GO:2000822 IMP involved_in regulation of behavioral fear response 21423165 Process
58234 GO:2000969 IMP involved_in positive regulation of AMPA receptor activity 21423165 Process

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
58234 GO:0005515 IPI enables protein binding 15569713,16606358,26966193,28469556,28671696,28701918,29111324..... Function
58234 GO:0035255 IPI enables ionotropic glutamate receptor binding 15207857,16606358 Function
58234 GO:0097110 IPI enables scaffold protein binding 16606358 Function
58234 GO:0098919 IDA enables structural constituent of postsynaptic density 27161151 Function
58234 GO:0098919 IEP enables structural constituent of postsynaptic density 27161151 Function
58234 GO:0098919 IMP enables structural constituent of postsynaptic density 27161151 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
58234 GO:0005886 IDA located_in plasma membrane 16606358 Component
58234 GO:0043005 IDA located_in neuron projection 21795692 Component
58234 GO:0044309 IDA located_in neuron spine 16606358 Component
58234 GO:0098978 IDA is_active_in glutamatergic synapse 27161151 Component
58234 GO:0098978 IEP is_active_in glutamatergic synapse 27161151 Component
58234 GO:0098978 IMP is_active_in glutamatergic synapse 27161151 Component