Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 5868
  • Symbol: RAB5A
  • Description: RAB5A, member RAS oncogene family

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5868 GO:0003924 IDA enables GTPase activity 15378032,17562788,24891604 Function
5868 GO:0005515 IPI enables protein binding 7957092,9697774,10491193,11870209,15016378,15207266,15328530,1..... Function
5868 GO:0005525 IDA enables GTP binding 15378032 Function
5868 GO:0019003 IDA enables GDP binding 15378032,23382462 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5868 GO:0005654 IDA located_in nucleoplasm Component
5868 GO:0005737 IDA located_in cytoplasm 18034774,21266579 Component
5868 GO:0005769 IDA located_in early endosome 15078902,15378032,17562788,18767904,21645192,24334765,25869668..... Component
5868 GO:0005829 IDA located_in cytosol 23382462 Component
5868 GO:0010008 IDA located_in endosome membrane 15016378,22431521 Component
5868 GO:0036477 IDA located_in somatodendritic compartment 16141272 Component
5868 GO:0043195 IDA located_in terminal bouton 16141272 Component
5868 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component
5868 GO:0070062 HDA located_in extracellular exosome 20458337 Component
5868 GO:0098559 IMP located_in cytoplasmic side of early endosome membrane 23382462 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5868 GO:0006897 IDA involved_in endocytosis 15378032 Process
5868 GO:0036465 IDA involved_in synaptic vesicle recycling 16141272 Process
5868 GO:0044788 IMP involved_in modulation by host of viral process 19376974 Process
5868 GO:0045022 IMP involved_in early endosome to late endosome transport 17562788 Process
5868 GO:0045921 IMP involved_in positive regulation of exocytosis 19966785 Process
5868 GO:0051036 IMP involved_in regulation of endosome size 17562788 Process
5868 GO:0051489 IDA involved_in regulation of filopodium assembly 14978216 Process
5868 GO:0150093 IGI involved_in amyloid-beta clearance by transcytosis 26005850 Process
5868 GO:2000286 IMP involved_in receptor internalization involved in canonical Wnt signaling pathway 16890161 Process
5868 GO:2000300 IMP involved_in regulation of synaptic vesicle exocytosis 16141272 Process