Gene Ontology

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 59272
  • Symbol: ACE2
  • Description: angiotensin converting enzyme 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
59272 GO:0001618 IDA enables virus receptor activity 16051304,18343844,33000221,33082294,33163980,33713620,36228039..... Function
59272 GO:0001618 IMP enables virus receptor activity 24227843 Function
59272 GO:0004175 IDA enables endopeptidase activity 15283675 Function
59272 GO:0004180 IDA enables carboxypeptidase activity 10924499,10969042,15283675,15380922,18258853 Function
59272 GO:0004181 EXP enables metallocarboxypeptidase activity 10924499,10969042,11815627 Function
59272 GO:0005515 IPI enables protein binding 10969042,11815627,14647384,15479853,15791205,18343844,18931070..... Function
59272 GO:0008237 IDA enables metallopeptidase activity 10924499 Function
59272 GO:0008241 IDA enables peptidyl-dipeptidase activity 10924499 Function
59272 GO:0042802 IPI enables identical protein binding 32275855,32678978,33262453,34867130 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
59272 GO:0003051 IMP involved_in angiotensin-mediated drinking behavior 18258853 Process
59272 GO:0003081 IMP involved_in regulation of systemic arterial blood pressure by renin-angiotensin 18258853 Process
59272 GO:0022898 IGI involved_in regulation of transmembrane transporter activity 25534429 Process
59272 GO:0046718 IDA acts_upstream_of_positive_effect viral entry into host cell 33163980 Process
59272 GO:0046718 IDA involved_in viral entry into host cell 16051304,32221306,33000221,33082294,33163980,33713620,36228039..... Process
59272 GO:0046813 IDA involved_in receptor-mediated virion attachment to host cell 18343844,32221306 Process
59272 GO:0051957 IMP involved_in positive regulation of amino acid transport 19185582 Process
59272 GO:0098670 IDA involved_in entry receptor-mediated virion attachment to host cell 36228039,36735681,36757924 Process
59272 GO:1903598 IMP involved_in positive regulation of gap junction assembly 12967627 Process
59272 GO:1903779 IMP involved_in regulation of cardiac conduction 12967627 Process
59272 GO:1905737 IGI involved_in positive regulation of L-proline import across plasma membrane 25534429 Process
59272 GO:2000272 IMP acts_upstream_of negative regulation of signaling receptor activity 18258853 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
59272 GO:0005576 IDA located_in extracellular region 10969042,33713620 Component
59272 GO:0005615 IDA located_in extracellular space 18258853 Component
59272 GO:0005886 IDA is_active_in plasma membrane 33163980,36228039,36735681,36757924 Component
59272 GO:0005886 IDA located_in plasma membrane 21068237 Component
59272 GO:0009986 IDA located_in cell surface 18343844,24227843 Component
59272 GO:0016324 IDA located_in apical plasma membrane 25534429 Component
59272 GO:0031526 IDA located_in brush border membrane 25534429 Component
59272 GO:0070062 HDA located_in extracellular exosome 19056867,23533145 Component